Project Grant R01NS146062
- The National Institute of Neurological Disorders and Stroke awarded Duke University $100,228 on December 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, assistance type: Project Grant F31NS149497). The project investigates cell-type-specific contributions of the primary somatosensory cortex to skilled forelimb control using two-photon calcium microscopy, optogenetic perturbation, genetic access to projection neuron types...
- The National Institute of Neurological Disorders and Stroke awarded Duke University $619,580 on April 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support research on neuronal kinase signaling in health and disease. The project integrates AI/ML algorithms, CRISPR-based proteomics, and in vivo models to investigate how kinases regulate neuronal physiology and contribute to neurodegenerative disease, with specific focus on...
- The National Institute of Neurological Disorders and Stroke awarded The University of Iowa $540,503 on May 7, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to conduct basic neuroscience research on cerebellar interactions with forebrain structures during associative learning. The research systematically analyzes how the cerebellum interacts with the anterior cingulate cortex and hippocampus during trace conditioning in rats....
- The National Institute of Neurological Disorders and Stroke, a component of the Department of Health and Human Services National Institutes of Health, awarded $120,582 to President and Fellows of Harvard College (operating as Harvard Medical School) on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining the functional specializations of cerebellar interneuron subtypes and their roles...
- Federal Project Grant Award Summary Duke University's Office of Research Administration received a $392,863 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective August 1, 2025, through July 31, 2026. The award supports the development of therapeutics for Spinocerebellar Ataxia Type 48 (SCA48), a neurodegenerative disease caused by mutations...
- The National Institute of Neurological Disorders and Stroke awarded Duke University $555,895 on July 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the biophysical mechanisms of temporal interference stimulation on epileptic discharges in the human brain. The research, conducted at the Comprehensive Epilepsy Center at Duke University in Durham, North Carolina, will leverage stereo-electroencephalography...
- The National Institute of Neurological Disorders and Stroke awarded The Trustees of Columbia University in the City of New York $150,932 on March 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop computational and theoretical models characterizing interactions between motor cortex and dorsolateral striatum in naturalistic motor behavior. The project uses simultaneous multi-region neural recordings from mice combined...
- The National Institute of Neurological Disorders and Stroke, an operating division of the National Institutes of Health under the Department of Health and Human Services, awarded $660,625 to the University of Connecticut Health Center on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the cellular and molecular mechanisms of cerebellar hemisphere development. The research will examine how different...
- The National Institute of Neurological Disorders and Stroke awarded Pennsylvania State University, operating as Penn State Milton S. Hershey Medical Center, $585,999 on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate cerebellothalamocortical communication and its role in cerebellar dysfunction. The research employs in vitro and in vivo experiments to characterize how the thalamus dynamically regulates...
- The National Institute of Neurological Disorders and Stroke awarded The Regents of the University of Colorado (doing business as University of Colorado-Denver) $535,124 on June 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to conduct research on neural circuits for disinhibition in the cerebellum. The funded work uses functional recordings, circuit-targeted activity manipulations, and behavioral analysis to determine how...
The National Institute of Neurological Disorders and Stroke awarded Duke University $478,336 on August 15, 2026, to investigate cortico-cerebellar interactions underlying goal-directed actions under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The research will examine how neural circuits in the brain, specifically interactions between the anterior lateral motor cortex and the cerebellum, give rise to goal-directed movement planning and execution. The project tests the hypothesis that the cerebellum learns to predict possible future actions within specific task contexts and engages these predictions during motor planning to shape cortical attractor dynamics. Work will include three aims: testing mice in multiple tasks while probing cortical attractors encoding future actions under different task contexts; performing brain-wide recordings from regions forming networks with the anterior lateral motor cortex and cerebellum to establish circuit basis of context-dependent signals; and testing the causal role of the cerebellum in shaping cortical attractor dynamics and the role of cerebellar plasticity in learning task context and predicted actions. Duke University's Office of Research Administration Division is the recipient. Performance occurs in Durham, North Carolina. The period of performance runs from August 15, 2026, through June 30, 2031. This is a Project Grant, a form of assistance funding supporting independent research projects.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $478.3k | 8/14/26 |