Project Grant K99NS146559
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $120,582 to President and Fellows of Harvard College on January 17, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating motor learning mechanisms in cortico-basal ganglia circuits. The project explores how neural circuits generate behavioral...
- The National Institute of Neurological Disorders and Stroke awarded $104,288 to President and Fellows of Harvard College on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). Harvard's Office for Sponsored Programs will develop a high-throughput molecular connectomics tool with synaptic resolution to map the molecular basis of synapse formation and specification. The work integrates neuronal wiring diagrams with...
- The National Institute of Neurological Disorders and Stroke awarded President and Fellows of Harvard College $579,740 on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). Harvard Medical School will conduct research to identify cell types and circuits that signal errors and their role in updating expectations for learning and cognitive flexibility. The work spans five years through March 31, 2031, performed in Boston,...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the Department of Health and Human Services National Institutes of Health, awarded $153,560 to the Broad Institute, Inc. (doing business as Broad Institute of MIT and Harvard) on December 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining how excitatory neurons regulate interneuron fate, position, and survival during...
- The National Institute of Neurological Disorders and Stroke awarded President and Fellows of Harvard College $151,352 on August 27, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate developmental activity and function of layer 5 cortical circuits following early postnatal reorganization. The research examines how inhibitory somatostatin-expressing cortical interneurons develop targeting specificity for distinct...
- The National Institute of Neurological Disorders and Stroke, an operating division of the National Institutes of Health under the Department of Health and Human Services, awarded $660,625 to the University of Connecticut Health Center on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the cellular and molecular mechanisms of cerebellar hemisphere development. The research will examine how different...
- The National Institute of Neurological Disorders and Stroke awarded the President and Fellows of Harvard College $636,084 on May 12, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate structural, functional, and molecular remodeling of an adaptive sensorimotor circuit. The research uses C. elegans male mating behavior as a paradigm to understand experience-dependent plasticity across a sensorimotor circuit...
- The National Institute of Neurological Disorders and Stroke awarded Duke University $478,336 on August 15, 2026, to investigate cortico-cerebellar interactions underlying goal-directed actions under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The research will examine how neural circuits in the brain, specifically interactions between the anterior lateral motor cortex and the cerebellum, give rise to goal-directed movement planning...
- The National Institute of Neurological Disorders and Stroke awarded the President and Fellows of Harvard College $120,501 on February 2, 2026, to elucidate the molecular and functional diversity of dorsal root ganglia somatosensory neurons across mammals under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The research investigates how somatosensory neuron types, sensory receptors, and cell-type-specific physiology vary across mammalian...
- The National Institute of Neurological Disorders and Stroke awarded President and Fellows of Harvard College $595,961 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate mitochondrial DNA mutations and gene editing approaches in neural dysfunction. The research addresses mechanisms of central nervous system dysfunction triggered by mitochondrial DNA (mtDNA) mutations, particularly mutations in...
The National Institute of Neurological Disorders and Stroke, a component of the Department of Health and Human Services National Institutes of Health, awarded $120,582 to President and Fellows of Harvard College (operating as Harvard Medical School) on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research examining the functional specializations of cerebellar interneuron subtypes and their roles in cerebellar circuit processing. The recipient will record and manipulate molecular layer interneuron (MLI) activity during cerebellum-dependent motor learning, characterize the contribution of MLI1 synchrony to ephaptic inhibition, and clarify the circuit properties and behavioral contributions of recently-identified interneuron subtypes (MLI1, MLI2, Golgi1, and Golgi2). The project includes investigation of gap junction protein connectivity, selective expression of connexin 36, and the disinhibitory roles of these interneuron populations in Purkinje cell output and predictive cerebellar processing. Work is performed at Boston, Massachusetts. The period of performance runs from August 15, 2026, through July 31, 2028. This is a project grant, the standard assistance type for NIH extramural research funding.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $120.6k | 8/13/26 |