Project Grant R01NS144287

Award Date 8/1/25
Completion Date 7/31/28
Dollars Obligated $425K
Funding Federal Agency
Office of the Director
Federal Grant Program
93.310
Assistance Type
Project Grant
Place of Performance
Sacramento, CA 95817, USA
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  1. Evaluate the natural history of sleep disruptions following acute organophosphate exposure
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  3. Identify biomarkers to predict long-term outcomes
  4. Evaluate the therapeutic potential of the dual-orexin receptor antagonist lemborexant to improve sleep and mitigate the development of seizures and cognitive deficits.

The award has a performance period from August 1, 2025 to July 31, 2028. This research aims to fill a critical unmet need in the field of countermeasures against chemical weapons exposure by identifying potential new targets for therapeutic intervention.

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