Project Grant R01NS143722
- This $400,000 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research by Baylor College of Medicine to investigate the contributions of spreading depolarization (SD) to epilepsy comorbidities and disease progression in Dravet syndrome, a major type of developmental epileptic encephalopathy. The project will leverage advanced...
- This Project Grant award for $158,324.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), supports research to investigate the mechanisms underlying seizures during acute viral infection and the development of chronic epilepsy in a mouse model of viral-induced temporal lobe epilepsy. The key products and services to be delivered include: quantifying...
- This federal Project Grant award of $414,305 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant will fund research to identify key molecules and pathways underlying the process of epileptogenesis, with the goal of developing therapies to modify disease progression. The research leverages a novel algorithm called MAGIC combined with a large...
- This federal Project Grant award of $238,356 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to study the role of the amygdala-nucleus reticularis thalami (NRT) pathway in modulating thalamocortical circuits and cortical activity, and its potential impact on seizures and neuropsychiatric comorbidities in people with epilepsy. The research, led by the...
- This $579,294 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research to understand the cell type-specific epigenetic mechanisms, particularly involving microRNAs, that regulate brain function and contribute to neurological disorders like epilepsy. The research aims to reveal the specific cell types and target mRNAs...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $426,250 Project Grant under CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders, to the Regents of the University of Minnesota, Office of Sponsored Projects Administration. This 2-year grant will fund research using cutting-edge voltage imaging to examine how interactions between specific neuronal circuit elements in the hippocampus relate to the development of temporal lobe...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $222,160 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of California, San Diego (UCSD). The grant will support Dr. Alena Stasenko's research to develop risk and resilience models of cognitive aging in epilepsy and novel, tech-based interventions to improve brain health. The project aims to leverage digital assessment to determine the...
- This federal Project Grant award of $225,599, awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research on the contributions of sex chromosomes versus gonadal hormones in shaping sex differences in epilepsy. The University of Illinois, the awardee, will utilize in vivo video-electroencephalography, RNA sequencing, and immunostaining to determine...
- This federal Project Grant award of $657,958 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is supporting research into the cellular and network mechanisms of epilepsy and neuromodulation. The research team from Trustees of Boston University will use cutting-edge cellular membrane voltage imaging, optogenetics, and local field potential recordings in cortical...
- This $1,309,206 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to investigate spatial recognition memory processes in patients with epilepsy. The goal is to develop improved cognitive assessments and treatments for the memory deficits commonly experienced by epilepsy patients, which are not well captured by current neuropsychological...
This $357,191 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program aims to mechanistically link acute seizures with chronic alterations in cholinergic networks in a mouse model of Dravet syndrome. The primary objective is to delineate seizure-associated pathology in the cholinergic pedunculopontine nucleus (PPN) to identify targets for next-generation therapeutics to treat the comorbidities of epilepsy, including attention deficits, mood disorders, cognitive impairment, and sleep disorders. The research will be conducted by the Regents of the University of Michigan from August 2025 to July 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $357.2k | 8/6/25 |