This $657,958 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will fund research to investigate the cellular and network mechanisms underlying epilepsy biomarkers and seizures, as well as the neuronal impacts of neuromodulation through electrical stimulation. The primary awardee, Trustees of Boston University, will utilize cutting-edge cellular membrane voltage imaging, optogenetics, and local field potential recordings in epilepsy mouse models to elucidate the mechanisms of epileptic activity, the relationship between spike ripples and seizures, and the effects of different electrical stimulation parameters on these biomarkers and seizures. The goal is to gain insights that can help improve treatment approaches for patients with drug-resistant epilepsy. The award period runs from June 1, 2025 to May 31, 2030.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $658.0k | 5/16/25 |