Project Grant R01NS141815
- This federal Project Grant award, valued at $400,000.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research at Baylor College of Medicine to investigate the contributions of spreading depolarizations (SDs) to epilepsy comorbidities and disease progression in Dravet syndrome, a major example of developmental epileptic...
- This $396,031 Project Grant award from the National Institute of Neurological Disorders and Stroke (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) will support research on G protein-coupled receptor (GPCR) trafficking and signaling in cardiomyocytes and neurons. The key objectives are to map the subcellular distribution of heterotrimeric G proteins, determine how G proteins move or redistribute upon GPCR activation, and develop bioluminescence...
- This $591,304 Project Grant was awarded on May 5, 2025 by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research at the University of Louisville focused on understanding the role of the integrated stress response pathway in cell-specific effects following traumatic spinal cord injury. Key goals of the research include investigating how...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) provides $671,988 to the Winifred Masterson Burke Medical Research Institute, Inc. to conduct research on the "Cross-Talk Between Sarmoptosis and Ferroptosis in Hemorrhagic Stroke". The research aims to better understand the cellular mechanisms that lead to axon degeneration in...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $423,500 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to the Augusta University Research Institute, Inc. The objective is to develop and evaluate engineered exosomes carrying neuron-targeting peptides and a therapeutic protein (neuroglobin) for treating ischemic stroke. The research will: 1) characterize the engineered exosomes and assess their...
- This federal Project Grant award of $158,324.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the mechanisms underlying acute seizures and the development of chronic epilepsy in a mouse model of viral encephalitis-induced temporal lobe epilepsy. The research team from the University of Iowa will quantify the...
- This federal Project Grant award of $234,750.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research on altered arterial smooth muscle in cerebrovascular dysfunction during aging. The research aims to investigate how changes in cell adhesion molecules, such as integrin A5B1 and N-cadherin, can contribute to excessive resistance artery...
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports innovative neuroscience research conducted by the J. David Gladstone Institutes in San Francisco, California. The $1,375,478 award will fund a multipronged research approach to understand the role of neurovascular dysfunction in neurodegeneration, CNS repair, and glial cell...
- This $657,958 federal Project Grant award was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award will fund a research project conducted by the Trustees of Boston University to investigate the cellular and network mechanisms underlying epilepsy biomarkers and the impact of neuromodulation on these mechanisms. The research will utilize advanced...
- This federal Project Grant award, valued at $376,355.00, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports research conducted by Albany Medical College to investigate the role of microglial insulin-like growth factor 1 (IGF1) in the pathological process of epileptogenesis, which transforms a normal brain into an epileptic brain. The...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program provides $462,933 to support research on spreading depolarization, a novel mechanism of injury in stroke and brain trauma patients. The research aims to reveal the role of volume-regulated chloride/anion channels (VRAC) in spreading depolarization-induced neuronal edema and recovery, as well as quantify in vivo mitochondrial calcium levels during spreading depolarization and their relationship to cell death or recovery. The award was granted to the Augusta University Research Institute, Inc., doing business as Georgia Health Sciences, and will run from January 1, 2026 to December 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $462.9k | 12/30/25 |