This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $817,345 to study the role of environmental stressors in the development of Alzheimer's Disease-Related Dementias (ADRD) across urban and rural populations. The primary awardee, Trustees of Indiana University, will recruit 600 participants from Indiana, 300 urban and 300 rural, who...
This federal Project Grant award of $1,625,947 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research to investigate the link between air pollution-derived iron exposure, poverty-related stress, and Alzheimer's disease risk. The key objectives of the research project are to: 1) evaluate whether exposure to ambient and subway-level concentrations of...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) seeks to examine the role of the "exposome" as a risk factor for Alzheimer's disease (AD) among non-Hispanic whites, African Americans, and Mexican Americans. The $1,205,827 project, awarded on August 1, 2024, will utilize blood samples from 3,000 participants in the ongoing Health & Aging Brain Study - Health Disparities Study. The goal is to identify environmental exposures that may...
This $502,929 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, aims to evaluate the impact of environmental heat and socioeconomic stressors, measured by the Heat Vulnerability Index (HVI), on stroke functional outcomes in individuals with Alzheimer's disease and related dementias (AD/ADRD). The research will be conducted by...
This Cooperative Agreement award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $2,278,304 to investigate the impact of fine particulate matter (PM2.5) exposure on the risk of developing Alzheimer's disease and related dementias (AD/ADRD). The primary awardee, Emory University, will characterize individual exposures to PM2.5 components, elucidate biological perturbations in brain, cerebrospinal fluid, and blood related to these toxicants, and determine the...
This $424,184 Project Grant award from the National Institute on Aging (NIA) under CFDA 93.866 (Aging Research) aims to study racial and ethnic disparities in access to Alzheimer's Special Care Units (SCUs) in nursing homes, and how disparities in SCU access may contribute to disparities in health outcomes for Black and Hispanic residents with Alzheimer's disease and related dementias (ADRD). The study will analyze national Medicare claims and nursing home assessment data from 2011-2019 to...
This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $2,329,825.00 to Emory University to investigate the relationship between air pollution exposure, blood/brain metabolic changes, and the development of Alzheimer's disease and related dementias. The project aims to identify the specific air pollutant components that are most neurotoxic, explore the role of other common air pollutants, and elucidate the biological mechanisms underlying the link...
The University of New Mexico Health Sciences Center was awarded a $3,925,264 Cooperative Agreement by the National Institute on Aging (CFDA 93.866 - Aging Research) to investigate the link between environmental exposures like microplastics, heavy metals, and wildfire smoke, and the incidence and progression of Alzheimer's disease and related dementias (ADRDs). The project, titled "PRE3BAD: Preclinical Research on Emerging Environmental Exposures, Brain Aging, and Dementia", will use...
This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $459,250 to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct research on the impact of stress and resilience on the progression of Alzheimer's disease (AD) pathology and cognitive function. The project will leverage longitudinal data from two large population studies to investigate the interplay between stress, resilience, AD...
This federal Project Grant award, valued at $5,262,301.00, was provided by the National Institute on Aging under the Aging Research program (CFDA 93.866) to Trustees of Boston University's Boston University Medical Campus. The grant will fund a 5-year research project titled "Improving Causal Inference in Alzheimer's Disease Prevention Research on Modifiable Risk Factors: The Triangulation of Innovative Methods to END AD (TIME-AD) Project - Overall Component." The project aims to...