Project Grant R01NS138465
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the U.S. Department of Health and Human Services, awarded a $663,942 Project Grant to Yale University under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The grant, awarded on July 25, 2025 with an ultimate completion date of June 30, 2030, supports research to examine the interplay between the synaptic proteins complexin and synaptotagmin and their...
- This federal Project Grant award, valued at $147,486, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The purpose of this award is to investigate the function of a ciliary protein in neural development, with a focus on uncovering novel molecular mechanisms involved in synapse formation that may be relevant to neurological disorders. Using C. elegans as...
- This $2,503,949 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Rockefeller University aimed at discovering therapeutic targets for neurological diseases. The project utilizes new techniques and concepts to study the fundamental mechanisms of brain disorders, focusing on how differences in cell-specific RNA regulation contribute to...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research to investigate the role of inhibitory synaptic nanostructure in inhibitory synaptic plasticity. The total award amount is $110,574.00 and the period of performance is from July 14, 2025 to November 30, 2027. The research will be conducted by the University of Colorado-Denver,...
- This Project Grant award of $148,040, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate how the cerebellar circuit's synaptic properties may underlie precisely timed behavioral outputs. The research project, led by the University of Colorado-Denver, will leverage optical tools to measure mossy fiber and granule cell...
- This federal Project Grant award of $501,125.00 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research to determine the mechanisms of dopamine transmission in the brain and how it regulates motor function and learning. The research aims to understand how different dopamine signals mediate transmission and impact aspects of motor activity and learning,...
- This Project Grant award, valued at $481,250.00 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a synthetic biological system to manipulate subcellular RNAs and proteins in growth cones or synapses of subtype- and context-specific neurons. The goal is to enable unique forms of subcellular functional investigation in subtype- and...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $551,250 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of California, Los Angeles (UCLA) to support research focused on understanding the molecular mechanisms underlying the formation of synaptic connections between neurons in the brain. The key research aims are to uncover the molecular basis of synaptic specificity in the...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,270,237 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the Icahn School of Medicine at Mount Sinai. The 5-year grant, effective August 1, 2025, will support a program to investigate the pathogenic mechanisms associated with neural disease in Congenital Disorders of Glycosylation (CDG). The program will utilize zebrafish, Drosophila, and human...
- This federal Project Grant award of $629,796 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award aims to track, quantify, and localize key metabolic pathways that regulate brain growth during development. Specifically, the project will investigate two critical metabolic switches in the developing mouse brain: (1) a shift from glycolytic to...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) provides $511,396.00 to Cedars-Sinai Medical Center to conduct research on understanding the diversity of presynaptic function among neuronal populations. The research aims to explore how differences in presynaptic machinery, such as synaptic vesicle replenishment pathways and protein homeostasis mechanisms, affect the properties of dopamine and glutamate neurotransmitter release. This 5-year award, running from August 1, 2025 to July 31, 2030, will advance knowledge on the molecular factors regulating neurotransmitter release probability and shed light on the diversity of presynaptic function across different neuronal systems.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $511.4k | 7/25/25 |