Project Grant R01NS144801
- This federal Project Grant award of $169,000 from the National Institute of Neurological Disorders and Stroke (NINDS, CFDA 93.853) will support the development of a comprehensive, open-source, and user-friendly online platform for neurometabolic diseases. The platform will include clinical, biochemical, radiological, and therapeutic data on over 1,600 known neurometabolic diseases. This initiative aims to enhance understanding, clinical management, and research insights into these rare genetic...
- This $491,163.00 Project Grant award was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award supports research conducted by the Icahn School of Medicine at Mount Sinai focused on understanding the role of plasma membrane properties and cytoskeleton mechanics in regulating neuroprogenitor cell differentiation and neurogenesis during...
- This Project Grant award, valued at $232,524, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award will support research at Stony Brook University to investigate the role of the AMPK signaling pathway in regulating energy production and usage during the myelination process in oligodendroglial cells. The goal is to better understand...
- This federal Project Grant award of $145,566 from the National Institute on Aging (CFDA 93.866 - Aging Research) is supporting research at the Icahn School of Medicine at Mount Sinai to investigate how the brain accumulates and utilizes "cognitive maps" - internal neural representations that enable flexible behavior and memory recall. The research aims to provide insights into the neuronal coding deficits underlying cognitive decline, with the goal of informing therapeutic...
- This $488,232 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, is funding research by The Washington University to explore the mechanisms by which astrocytes, a type of glial cell, support the metabolic needs of neighboring neurons in the brain. The 5-year project aims to investigate the regulation of intracellular and...
- This federal Project Grant award of $141,102 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative program (CFDA 93.372). The award supports research by New York University to study the role of astrocyte networks in facilitating neuroplasticity. Key objectives include mapping functional astrocyte networks across the brain using a novel biotinylation...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,270,237 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the Icahn School of Medicine at Mount Sinai. The 5-year grant, effective August 1, 2025, will support a program to investigate the pathogenic mechanisms associated with neural disease in Congenital Disorders of Glycosylation (CDG). The program will utilize zebrafish, Drosophila, and human...
- This federal Project Grant award of $115,327.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports research to investigate the protracted maturation of cortical inhibitory neurons (CINs) in the human brain and their contribution to regional cortical specification and vulnerability during the perinatal period. The research aims to...
- This federal Project Grant award of $459,000.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to understand the anatomical and physiological changes accompanying neocortical malformations known as molecular layer heterotopia (MLH). The research will utilize GPR56 knockout mice to study the neuronal and glial changes in MLH using spatial...
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $361,975 to support research focused on developing chemical strategies for imaging and manipulating astrocytes in the brain. The project aims to expand the capabilities of an astrocyte-targeting chemical tag to enable direct visualization and modulation of astrocyte...
This federal Project Grant award of $629,796 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award aims to track, quantify, and localize key metabolic pathways that regulate brain growth during development. Specifically, the project will investigate two critical metabolic switches in the developing mouse brain: (1) a shift from glycolytic to oxidative metabolism and (2) a biosynthetic switch from the propionate-to-succinyl-CoA pathway to pyruvate carboxylation. The award will fund research at the Icahn School of Medicine at Mount Sinai in New York to advance the understanding of cerebral metabolism during brain development and identify the biochemical pathways driving growth. The project period runs from August 1, 2025 to July 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $629.8k | 7/30/25 |