The National Institute of Mental Health (NIMH) awarded a $252,125 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to The Trustees of Columbia University in the City of New York to conduct research on the neural mechanisms underlying context-dependent decision-making. The research aims to use functional magnetic resonance imaging (fMRI) in mice to identify brain regions involved in maintaining contextual information to guide decisions, and then employ optogenetics...
The National Institute of Mental Health (NIMH) awarded a $1,401,862 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to the University of California, Berkeley. The 5-year grant, which commenced on September 21, 2024, will support research to investigate the role of the orbitofrontal cortex (OFC) in inhibiting habitual responses in the striatum to enable goal-directed decision-making. The researchers will use a novel behavioral task and advanced neural recording...
This Project Grant award of $608,309 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program will support research to understand the role of the claustrum, a poorly understood brain region, in flexible decision-making. The research aims to test whether claustrum neuron activity encodes decision variables in tasks requiring cognitive flexibility, determine if claustrocortical neurons are required for dynamic decision-making and reversal...
This federal Project Grant award of $389,735.00 was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program. The project aims to identify the neural correlates of mental simulation in multi-step planning, which is essential for decision-making and is often impaired in psychiatric and neurological disorders. The research team at New York University will use a combination of fMRI, MEG neuroimaging, and eye-tracking to study the...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program provides $1,978,475.00 in funding from August 6, 2024 to April 30, 2029 to investigate the neural basis of visual attention in the primate brain. The grant supports research conducted by The Trustees of Princeton University to uncover the neural mechanisms underlying the rhythmic, theta-based sampling of visual information during attentional...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is providing $107,948.00 to The Johns Hopkins University to study the computational mechanisms underlying single neuron activity within brain-wide circuits. The research aims to characterize the relationships between synaptic input patterns and action potential generation in cortical neurons, investigate how inputs change when the brain drives specific neuron...
The National Institute of Mental Health (NIMH) awarded a Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Weill Medical College of Cornell University for $582,953. The project, titled "The KrackenCoder: A Multi-Modal Connectome Fusion Tool for Brain-Behavior Mapping," aims to create and validate computational tools that integrate and estimate multi-modal brain connectivity data across many individuals, with and without diagnoses, in a behaviorally relevant...
The federal Project Grant award R01MH139352, totaling $429,323.00, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program. The grant supports research to investigate cognitive flexibility and the neural mechanisms underlying cognitive thalamocortical dynamics, with the goal of advancing understanding and treatment of mental illnesses characterized by cognitive inflexibility, such as schizophrenia. The primary awardee is New...
The National Institute of Mental Health (NIMH) awarded a $6,436,100 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to Princeton University for the "CONTE CENTER: UNDERSTANDING LATENT CAUSE INFERENCE IN HEALTH AND ILLNESS" on Aug 12, 2024. This research program aims to conduct a comprehensive investigation of latent cause inference, a fundamental cognitive process, and its relationship to mental health symptoms and disorders. The project involves four...
The National Institute of Mental Health (NIMH) awarded a $314,113 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to Physical Sciences Inc. (PSI) of Andover, MA. The grant will fund the development and demonstration of a high-speed, multicolor confocal fluorescence imager to simultaneously capture multi-wavelength signals and display them as separated or merged multicolor images and 3-D stacks. This technology innovation will enable mapping of complex neuronal network...