Project Grant R01MH138582
- The National Institute of Mental Health (NIMH) awarded a $792,441 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to The Mclean Hospital Corporation in Belmont, MA. The grant, awarded on April 15, 2025, will support a research project titled "Tracking the Dynamic Trajectory of Behavioral, Physiological, and Neurobiological Stress Responses in Female Adolescents at High and Low Familial Risk for Depression." The project aims to investigate how parental...
- The National Institute of Mental Health (NIMH) awarded a $147,486 Project Grant under the Mental Health Research Grants program (CFDA 93.242) to the University of Oregon on September 28, 2025. This longitudinal study examines the linkages between neighborhood environment, puberty, sleep quality, and trajectories of depression in adolescent girls. The research aims to 1) identify the direct effects of neighborhood factors on depression, 2) investigate the mediating/moderating role of pubertal...
- This federal Project Grant award, titled "Tracking Depression and Associated Modifiable Social-Emotional Factors in Adolescent Girls with Autism", is funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The award provides $509,310.95 to the University of Texas at Austin to conduct a longitudinal study investigating depression trajectories and social mechanisms among adolescent girls with autism spectrum disorder. The...
- This Project Grant award of $2,285,036 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support a study on the impact of parental income on child mental health and neuroimmune function. The study leverages a randomized controlled trial to experimentally examine the causal pathways from family income to mental illness via family stress and neuroimmune mechanisms. The 5-year project will follow a sample of 1,200 youth with...
- This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), aims to leverage population-level data to inform the prevention and treatment of adolescent depression following adverse childhood experiences (ACEs). The $458,177 award to the University of California, San Francisco will support a robust, well-powered, data-driven analysis to identify combinations of factors that affect the association between ACEs and...
- This federal Project Grant award of $734,220.00 from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), supports research to investigate the impact of early life adversity on positive affect and its neural mechanisms in relation to depression risk. The project aims to: (1) determine if there is a reduction in the behavioral persistence or intensity of positive affect for youth exposed to adversity, (2) examine if individual...
- This Project Grant award of $919,453 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research to identify the immunobiological mechanisms underlying the development of depression during the perimenopause transition in women. The project aims to determine plasma tryptophan metabolite and cytokine patterns in perimenopausal depression, define epigenetic mechanisms in lymphocytes that confer vulnerability to developing...
- This $136,113 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research on the neural mechanisms underlying the co-occurrence of depression and anxiety in adolescents. The research aims to use advanced network analysis techniques to identify disturbances in brain networks that are shared by emerging depression and anxiety, providing critical insights into the prevention and treatment of these mental...
- This federal Project Grant award of $768,260.00 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is funding a project titled "Improving the Treatment of Depression among Youth with HIV" at Rhode Island Hospital, a division of Lifespan Corporation. The goal of the project is to train clinicians in a tailored, measured-care approach combining cognitive behavioral therapy and medication management to effectively reduce...
- This federal Project Grant award of $1,440,659, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), is funding the development and testing of a novel group intervention called "Perinatal Dialectical Behavior Therapy Skills (DBT-P)" to address emotion dysregulation during pregnancy. The goal is to improve maternal emotion regulation skills, with the aim of positively impacting infant neurobehavioral and...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $853,969 to investigate trajectories of maternal depression over a 25-year period among low-income families in the United States. The research project, awarded to Trustees of Indiana University, will leverage an existing longitudinal study to examine how sociodemographic characteristics, child developmental stages, and contextual risk/protective factors relate to depression trajectories. The study will also evaluate whether a family-centered intervention, the Family Check-Up, can mitigate the severity of depressive symptom trajectories. The award period runs from September 24, 2025 to July 31, 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $854.0k | 9/24/25 |