This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $197,660 in funding to Duke University to conduct research on characterizing early signs of neurobehavioral dysregulation in infants at increased risk for behavioral disorders. The key objectives of this 2-year project are to: 1) leverage data integration and advanced statistical techniques to identify modifiable mechanisms that increase risk...
This Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) provides $415,000 to the University of Colorado-Denver to develop and test a single-session cognitive behavioral intervention to prevent perinatal mood, anxiety, and trauma symptoms in high-risk pregnant patients requiring cesarean delivery. The intervention, called the Brief Exposure to the Operating Room (BE-OR), aims to reduce anxiety...
This Project Grant award of $689,409 from the National Institute of Child Health and Human Development (NICHD) under CFDA Program 93.865 - Child Health and Human Development Extramural Research will support a clinical translational study to determine the role of the microbiota-gut-brain axis (MGBA) in perinatal depression (PND). The 5-year study will recruit 158 racially diverse pregnant women to investigate how interactions between maternal and microbial systems influence depressive symptom...
The National Institute of Mental Health (NIMH) awarded a $2,295,419 Project Grant (CFDA 93.242 - Mental Health Research Grants) to Yale University to conduct a clinical trial of a Mindfulness-Based Neurofeedback (MBNF) intervention. The goal is to evaluate if MBNF can augment Dialectical Behavior Therapy (DBT) skills group training for adults with Borderline Personality Disorder (BPD). The study aims to determine if MBNF can strengthen brain circuitry supporting mindfulness and amplify the...
This federal Project Grant award of $418,178 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to provide mechanistic insights into the neurobiological mechanisms by which maternal sensitivity is compromised by postpartum depression. Specifically, the University of Massachusetts (UMass), through its Office of Grant & Contract Administration, will use intersectional viral...
This $790,712 Project Grant, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), aims to experimentally test the hypothesis that maternal encouragement of child positive emotion will lead to increases in child neural reward response. The grant will support a randomized controlled trial that will train 180 mothers with depression symptoms on positive emotion coaching through the Parent-Child Interaction Therapy-Emotion...
The National Institute of Mental Health (NIMH) awarded a $256,627 Project Grant (CFDA 93.242 - Mental Health Research Grants) to the University of Denver to develop and pilot a brief digital intervention for parents of pre- and early adolescents targeted at improving their skills in emotion regulation, validation, and suicide-specific monitoring. The goal is to support parents in responding effectively to suicide risk alerts generated by digital monitoring apps, thereby reducing...
This Project Grant award from the National Institute of Mental Health (NIMH, CFDA 93.242 Mental Health Research Grants) supports research to determine how cortico-insular connectivity is related to emotion dysregulation and affected by brain stimulation. The $123,833 award to Duke University, with a performance period from Sep 30, 2024 to Apr 30, 2027, will employ a connectomic approach to advance scientific knowledge about the role of functional and structural insular networks in...
This federal Project Grant award, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), aims to improve the effectiveness of parenting interventions for early childhood mental health concerns. The $561,325 grant, awarded on May 1, 2024, will enable the principal investigator to conduct research with the ultimate goal of becoming an independent scientist focused on enhancing parenting interventions. The key objectives are to: (1)...
This $2,278,274 federal Project Grant award from the National Institute of Mental Health (CFDA 93.242 - Mental Health Research Grants) aims to characterize brain changes across pregnancy using advanced multimodal magnetic resonance imaging (MRI). The primary goals are to: 1) determine the magnitude and pattern of changes in brain structure and function over the course of pregnancy; 2) investigate the hormonal changes underlying these brain alterations; and 3) examine the potential functional...