This Project Grant award from the National Institute of Mental Health (NIMH), under the federal Mental Health Research Grants program (CFDA 93.242), is funding a research project to investigate the circuit mechanisms underlying interactions between distinct learning systems. The $1,425,651 award, with a start date of July 18, 2024 and an ultimate completion date of March 31, 2029, is being provided to the University of Maryland, Baltimore to conduct this multi-level, interdisciplinary...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $338,600 to The Trustees of Columbia University in the City of New York, from August 1, 2024 to June 30, 2027. The project aims to use computational modeling and human single-neuron recordings to demonstrate the neural circuits that underlie egocentric and allocentric cognitive maps in humans. The research will analyze how spatial cells...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA program 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders, provides $234,310 to the Icahn School of Medicine at Mount Sinai to conduct research on the impact of the timing of inputs from the medial entorhinal cortex (MEC) to the hippocampus on spatial memory performance in healthy and epileptic mice. The research will use a closed-loop...
This Project Grant award from the National Institute of Mental Health (NIMH), under CFDA Program 93.242 Mental Health Research Grants, will support research to investigate the role of reward mechanisms in memory formation within the hippocampus. The $242,310 award to The Johns Hopkins University will fund in vivo electrophysiology studies to evaluate how expected and unexpected rewards influence head scanning behavior and place field potentiation in hippocampal regions CA1 and CA3. The project...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $677,261 to the University of New Mexico Health Sciences Center (UNM HSC) to conduct research on "Locus Coeruleus Regulation of Hippocampal Network Reset During Learning." The goal is to establish a causal role of the hippocampal-locus coeruleus loop in fostering behavioral flexibility by facilitating transitions between hippocampal...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is funding research by Northwestern University to investigate the microcircuit mechanisms behind the distributed cortical contributions to working memory in mice. The $553,788 award, granted on January 1, 2025 with a final completion date of December 31, 2029, will allow the researchers to use simultaneous two-photon calcium imaging and optogenetic...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to understand the functional differentiation of dorsal and ventral hippocampal place cell populations in rats. The $232,183 award to the University of Texas at Austin aims to determine whether coordinated place cell sequences in the dorsal and ventral hippocampus code for spatial trajectories at different scales, and whether ventral...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $649,965 to The Regents of the University of California, San Francisco (UCSF) over a 5-year period from December 1, 2024 to October 31, 2029. The funding supports research to identify the specific connections between the basolateral amygdala (BLA) and ventral hippocampus (VHPC) that generate synchronous beta-frequency activity, and to study how...
This Project Grant award from the National Institute of Mental Health (CFDA 93.242 - Mental Health Research Grants) is providing $495,907 to Florida State University (FSU) from September 1, 2024 to August 31, 2026. The goal of the research is to understand the neurobiological basis of how the brain coordinates spatial memories and actions during navigation. Specifically, the project aims to: 1) Determine if the hippocampus-parietal cortex circuit encodes both map-like and action-based spatial...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under CFDA 93.242 Mental Health Research Grants supports research to understand the neurobiological basis of schizophrenia and its impact on hippocampal network dynamics and spatial memory. The $231,547 award to George Mason University, a prominent research university, aims to investigate how NMDA receptor signaling regulates hippocampal oscillations and spatial memory retrieval. The study uses transgenic...