This federal Project Grant award from the National Institute of Mental Health (CFDA 93.242 Mental Health Research Grants) provides $446,627 to the University of California, San Diego to conduct research on the function of the subiculum region of the brain and its role in spatial cognition and navigation. The research aims to systematically investigate orientation tuning and encoding of directional information in the subiculum, with a focus on how this brain region supports flexible navigation...
This Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research conducted by the Research Foundation For Mental Hygiene, Inc. (RFMH) to examine the microcircuitry of cue and spatial representations in the dentate gyrus region of the hippocampus. The $489,197 award, spanning July 1, 2025 to June 30, 2030, will leverage in vivo...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will support research on the mechanisms and functions of temporal coordination in the entorhinal-hippocampal network. The total funding amount is $571,694, with the award period running from September 23, 2024 to June 30, 2029. The research aims to elucidate how the fine temporal coordination of neuronal activity across entorhinal and hippocampal...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research on the role of reward mechanisms in episodic memory formation within the hippocampus. The $242,310 award to The Johns Hopkins University will fund in vivo electrophysiology studies to examine how rewards, including expected and unexpected rewards, influence head scanning behavior and the potentiation of hippocampal place cells across the CA1...
This federal Project Grant award of $389,735.00 was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program. The project aims to identify the neural correlates of mental simulation in multi-step planning, which is essential for decision-making and is often impaired in psychiatric and neurological disorders. The research team at New York University will use a combination of fMRI, MEG neuroimaging, and eye-tracking to study the...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders provides $223,176 to The Leland Stanford Junior University to conduct research on the convergence of top-down and bottom-up thalamic inputs in the medial entorhinal cortex (MEC). The research aims to elucidate how flexible transformations of MEC spatial representations are orchestrated by neural circuits...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to investigate the functional differentiation of place cell populations in the dorsal and ventral hippocampus of rats. The $232,183 award, with a project period from January 13, 2025 to December 31, 2026, will enable researchers at the University of Texas at Austin to use state-of-the-art neurophysiological methods to record place cell...
The National Institute of Mental Health (NIMH) awarded a $431,750 Project Grant (CFDA 93.242 - Mental Health Research Grants) to the University of California, Irvine (UC Irvine) to investigate the role of the medial striatum in spatial sequence learning and its interaction with the hippocampus. The two-year study, running from September 1, 2023 to August 31, 2025, aims to evaluate how the dorsomedial striatum contributes to the disambiguation of repeated spatial traversals that occur in distinct...
This $1,338,397 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will fund research to understand spatial representations in the orbitofrontal cortex (OFC) of rats and their role in value-based decision making. The primary awardee, the University of California, Los Angeles (UCLA), will develop two novel behavioral tasks for rats that require spatial credit assignment - the "patch-leaving task" and...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $781,119 to the University of California, San Francisco to conduct research on the neural population dynamics that represent unconditioned and conditioned stimuli in the ventral hippocampus. The 5-year project aims to leverage anatomical targeting, large-scale population recording, computational tools, and cell-type specific manipulation to...