Project Grant R01HL184157
- Federal Project Grant Summary Award Details: Pulseimaging.ai, LLC received $304,415 in federal funding under the National Heart, Lung, and Blood Institute's (NHLBI) Cardiovascular Diseases Research program (CFDA 93.837). The award was obligated on August 15, 2025, with a completion date of August 14, 2027. Products and Services: The awardee will develop an artificial intelligence-enabled software solution designed to predict future cardiovascular events from screening CT calcium score (CTCS)...
- Federal Project Grant Award Summary Case Western Reserve University's Office of Research Administration, in affiliation with University Hospitals of Cleveland, received a $109,076 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 30, 2025, with completion targeted for September 29, 2029. The award funds research to advance cardiovascular risk prediction through detection and...
- Federal Grant Award Summary Cleveland Clinic Lerner College of Medicine of Case Western Reserve University received a $1,537,726 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 3, 2025, with completion targeted for May 31, 2029. The award funds demonstration of feasibility for AutoCMR (autonomous cardiac magnetic resonance imaging), a push-button, time-resolved 3D cardiac MRI protocol...
- Federal Project Grant Award Summary Case Western Reserve University, in affiliation with University Hospitals of Cleveland, received a $760,476 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective July 1, 2026, through April 30, 2030. The award supports the development of a low-field magnetic resonance imaging (MRI)-guided robotic catheter system designed to improve outcomes in ventricular tachycardia...
- Federal Grant Award Summary Invia LLC received a $1,107,749 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) to develop deep learning tools for the diagnosis of coronary microvascular and vasomotor dysfunction (CMVD). The project, which runs from September 5, 2025, through August 31, 2027, focuses on creating artificial intelligence methods and computer software tools capable of noninvasive diagnosis and...
- Federal Project Grant Award Summary Case Western Reserve University's Office of Research Administration received a $1.53 million Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded July 1, 2026, with completion targeted for May 31, 2028. The award funds research and development of a novel "bait-and-switch" gene therapy delivery platform designed to overcome critical barriers in...
- Federal Project Grant Award Summary The University of Pittsburgh received a $593,985 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 15, 2025, with completion targeted for June 30, 2029. The project develops artificial intelligence (AI) techniques and systems that convert photoplethysmography (PPG) measurements from off-the-shelf wearable devices into multi-lead electrocardiogram (ECG)...
- Federal Project Grant Award Summary Case Western Reserve University's Office of Research Administration, in affiliation with University Hospitals of Cleveland, received a $2.74 million Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) effective July 15, 2026, with anticipated completion by June 30, 2028. The award supports basic research to elucidate the molecular mechanisms by which cardiac myosin binding...
- Federal Grant Award Summary Emory University received a $153,638 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective March 7, 2026, through September 6, 2027. The project investigates the development and validation of an electrocardiogram (ECG)-based artificial intelligence (AI) deep learning model designed to predict coronary artery calcium (CAC) and identify individuals at elevated risk for...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a $429,000 Project Grant to the Regents of the University of Michigan on August 15, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop a rapid, non-contrast, low-field magnetic resonance imaging (MRI) pipeline for detecting pulmonary embolism (PE). The project, which extends through July 31, 2027, focuses on creating an efficient 3D, contrast-free MRI protocol utilizing...
Case Western Reserve University, in affiliation with University Hospitals of Cleveland, received a $1,573,126 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded July 15, 2026, with completion targeted for March 31, 2028. The award funds development of an artificial intelligence (AI)-based clinical decision support tool designed to optimize the use of advanced ischemia imaging in patients with elevated coronary artery calcium burden. The tool will integrate readily available, low-cost data sources—including coronary artery calcium scoring computed tomography (CT), electrocardiogram (ECG) readings, and clinical risk factors—to identify patients at risk of myocardial ischemia who would benefit from advanced diagnostic imaging such as stress positron emission tomography (PET), single-photon emission computed tomography (SPECT), cardiac magnetic resonance imaging (MRI), echocardiography, or coronary CT angiography with fractional flow reserve derived from CT (FFRCT). This decision support tool addresses a critical clinical need by establishing standardized guidance for ordering advanced imaging tests, reducing unnecessary testing (which currently yields ischemia identification in only 3-6% of cases), and improving resource allocation in cardiovascular disease screening and management. The research leverages the scientific premise that atherosclerosis burden correlates with ischemia risk and builds upon preliminary data supporting ischemia prediction using CT calcium scoring and electrocardiographic data. The project directly supports NHLBI's mission to foster translational and clinical research advancing cardiovascular disease prevention and treatment.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.6m | 7/16/26 |