Project Grant R01HL184168
Award Date 9/15/25
Completion Date 6/30/29
Dollars Obligated $300K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Pittsburgh, PA 15222, USA
Similar Awards
- The University of Pittsburgh was awarded a $791,485 Project Grant from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) on August 1, 2025. The grant will support research on "Treatment of Post-Infarction Cardiac Remodeling Using Image-Guided Delivery of MicroRNA-Loaded Microbubbles and Ultrasound-Mediated Cavitation". The research aims to develop an innovative ultrasound-based approach for targeted delivery of anti-microRNA-92a therapy to...
- The U.S. National Heart, Lung, and Blood Institute, through the Cardiovascular Diseases Research federal grant program (CFDA 93.837), awarded a $406,221 Project Grant to the Florida Institute of Technology Inc. (Florida TECH) on September 15, 2025. The grant supports the development of a novel, low-cost, machine learning-based and wearable technology for continuous monitoring of heart failure parameters, such as left ventricular function. The project aims to address the gap in remote cardiac...
- The federal Project Grant award, titled "Focal Myocardial Delivery of Small Molecule Nitroalkenes Using Ultrasound Targeted Microbubble Cavitation to Improve Ventricular Recovery Following Myocardial Infarction," was awarded by the National Heart Lung and Blood Institute under CFDA 93.837, the Cardiovascular Diseases Research program. The $720,676 award, with a start date of March 4, 2025 and an ultimate completion date of December 31, 2028, aims to develop a novel therapeutic strategy...
- The University of Pittsburgh was awarded a $633,045 project grant by the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to investigate the pathogenic mechanisms and therapeutic approaches for exercise intolerance in post-acute sequelae of COVID-19 (PASC). The project aims to elucidate the molecular drivers of exercise intolerance in PASC patients, leveraging the university's expertise in evaluating PASC patients at their post-COVID recovery clinic. Key...
- This $726,205 federal Project Grant awarded by the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports the development and validation of a new super-resolution intravascular ultrasound (SR-IVUS) technology. The goal is to enable effective imaging of the coronary vasa vasorum network and thin fibrous cap of vulnerable atherosclerotic plaques to better assess plaque vulnerability and prevent acute coronary syndromes. The project involves creating an...
- The University of Pittsburgh was awarded a $1,546,880 Project Grant from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) on January 1, 2025. The grant, titled "E-Box Accessibility in Myofibroblasts in Pulmonary Fibrosis", aims to investigate the regulatory mechanisms underlying the myofibroblast program in idiopathic pulmonary fibrosis (IPF). The research will employ novel techniques like single nucleus ATAC-seq and massively-parallel...
- This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will support a study examining the link between stressful life events and cardiovascular disease (CVD) risk. The $156,858 award, granted on February 1, 2025, will enable the University of Pittsburgh to utilize deidentified data from 656 healthy adults to investigate how brain and behavioral measures of negative affect and cognitive reappraisal...
- The University of Pittsburgh has been awarded a $438,137 Project Grant from the National Science Foundation (NSF) Engineering program (CFDA 47.041) to develop a microfluidic technology to model the interactions between macrophages and epithelial cells in a 3D environment under hypoxic conditions. The goal is to advance the fundamental understanding of how oxygen levels impact key cellular processes in macrophages, such as migration and proinflammatory cytokine production. This research will also...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $754,729 to the University of Pittsburgh to investigate the mechanisms by which respiratory viral infections, including COVID-19, can lead to persistent lung inflammation and damage. The research aims to understand how viral antigen persistence in pulmonary endothelial cells drives chronic activation of CD8+ T cells, leading to long-term pulmonary sequelae. The...
- This federal Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $616,864.00 to the University of Pittsburgh to conduct research on optimizing maternal health and reducing cardiovascular disease (CVD) risk factors during the perinatal period. The project, titled "Optimizing Maternal Health: Assessing Sleep-Based Strategy Enhancement of Diet, Physical Activity and Self-Regulation Interventions in Perinatal Health -...