Project Grant R01HL184156
- Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) awarded a $1.41 million Project Grant to the University of Colorado-Denver, with performance running from September 1, 2025, through May 31, 2030. This ancillary study investigates the impact of pregnancy microbiomes on maternal and child cardiovascular health outcomes in a racially and ethnically diverse cohort. The research addresses a critical public...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded $134,982 to The Regents of the University of California, San Francisco through the Cardiovascular Diseases Research program (CFDA 93.837) on September 5, 2025, with completion scheduled for June 30, 2027. This project grant funds basic biomedical research investigating the genetic and nutritional control of sleep across seasonal variations. The research aims to elucidate how circadian clock...
- Federal Grant Award Summary Brigham Young University received a $568,125 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 5, 2025 through August 31, 2028. The grant funds a comprehensive sleep neuroimaging research study titled "The Role of Local Sleep Disturbance in Obesity Risk: A Sleep Neuroimaging Study." The research employs advanced functional magnetic resonance...
- Federal Project Grant Award Summary Remastered Sleep LLC received $316,609 in funding from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) for a project addressing obstructive sleep apnea (OSA) in infants. The award, dated September 15, 2025, with completion expected by August 30, 2026, supports the development of a novel myofunctional nipple device designed to prevent OSA in infants through non-invasive means. This...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a $616,864 Project Grant on September 3, 2025, to the University of Pittsburgh to conduct a mixed-methods research study examining sleep-based strategies as an enhancement to diet, physical activity, and self-regulation interventions for optimizing maternal health and reducing cardiovascular disease (CVD) risk during the perinatal period. The research leverages existing trial data from the Health...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), awarded Colorado State University a $1.89 million Project Grant on September 15, 2025, to develop and validate electrical impedance tomography (EIT) as a noninvasive diagnostic tool for assessing respiratory function in patients with muscular dystrophies. The project, extending through June 30, 2030, addresses a critical clinical gap by providing an...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of Denver a Project Grant totaling $169,638 (awarded July 15, 2026) under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate the relationship between neighborhood food access and cardiovascular disease (CVD) risk in early childhood. The research leverages two prospective cohorts—the geographically diverse Environmental Influences on Child Health Outcomes (ECHO) cohort...
- Federal Grant Award Summary Brigham & Women's Hospital received a $1,668,762 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 1, 2025, with completion targeted for May 31, 2029. The project, "Leveraging Research and Clinical Cohorts to Improve Obstructive Sleep Apnea Subtyping," aims to develop physiologically informative metrics for obstructive sleep apnea (OSA) that...
- Federal Project Grant Award Summary The University of Utah received a $730,993 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 1, 2025, through May 31, 2030. This research project investigates the mechanistic contribution of internal circadian misalignment to cardiometabolic risk associated with sleep loss. The research addresses a significant public health challenge, as over...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded $150,104 to the Regents of the University of Colorado (University of Colorado-Denver) on January 26, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837). The project, titled "Lysine Myristoylation as a Novel Mechanism for Regulating PKA in the Heart," will be completed by December 31, 2028. The research investigates an alternative mechanism to activate protein kinase A (PKA)...
Colorado State University's Sponsored Programs division received a $785,172 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective July 5, 2026, with completion targeted for March 31, 2030. The award funds longitudinal research investigating the independent and interactive effects of sleep patterns and gut microbiota on rapid weight and fat gain in infants and toddlers during the critical "first 1000 days" developmental window. This research addresses a significant public health concern, as rapid weight gain during infancy is a major driver of childhood obesity and metabolic syndrome development. The deliverables include comprehensive, frequent longitudinal assessments employing objective sleep measurement via actigraphy and sleep diaries, gut microbiota characterization using 16S ribosomal RNA (rRNA) sequencing and fecal metabolomics analysis, and quantitative body composition and growth measurements. The research builds on pilot studies demonstrating associations between infant sleep parameters and both microbiota composition and growth trajectories, as well as evidence that fecal transplants from rapidly gaining infants increase fat accumulation in animal models. The project outputs will identify modifiable, non-invasive health targets for preventing rapid weight and fat gain in the infant population.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $785.2k | 7/7/26 |