Project Grant R01HL178934
- This $691,124.00 project grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research on the relationship between circadian disruption and cardiometabolic risk during the transition from adolescence to young adulthood. The project aims to test the hypothesis that persistent circadian disruption, including misaligned sleep, eating, and activity timing, will be related to the development of cardiometabolic risk through epigenetic...
- This federal Project Grant award for $743,388, awarded by the National Heart, Lung, and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), supports research on the mechanisms by which sleep loss and circadian misalignment contribute to insulin resistance and the development of Type 2 diabetes mellitus. The award will fund two randomized controlled trials with 48 adult participants to characterize the role of cortisol rhythms and downstream metabolomic and endocrine...
- This federal Project Grant award, totaling $1,621,874.00, was provided by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837) with an award date of Sep 23, 2025 and an ultimate completion date of Jun 30, 2027. The award was granted to Brigham & Women's Hospital Inc., a subsidiary of the larger Partners Healthcare System (now Mass General Brigham), to conduct research on the role of ambient lighting in circadian misalignment and its...
- This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $134,982 to The Regents of the University of California, San Francisco (UCSF) to conduct research on the genetic and nutritional control of sleep across seasons. The overarching goal is to investigate how the circadian clock and seasonal variations in light and nutrients impact sleep and feeding behaviors. Key activities include analyzing sleep, feeding,...
- This federal Project Grant award, provided by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), will fund research to investigate place-based factors contributing to sleep health disparities in the United States. The $177,385 award to Brigham & Women's Hospital Inc., a subsidiary of Partners Healthcare System, will: 1) Estimate sleep health measures and environmental circadian misalignment across different populations and geographies; 2) Examine...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $385,033 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Oakwood University, Inc. in Alabama. The grant will fund research to investigate how circadian rhythm disruptions, such as from fragmented day-night cycles, impact sleep patterns and binge-like eating behavior in mice. The project aims to examine the neurological mechanisms underlying how the brain responds to changes in light-dark cycles...
- This Project Grant award of $790,584.00 from the National Heart, Lung, and Blood Institute (CFDA Program 93.837 - Cardiovascular Diseases Research) supports research to determine the optimal duration of overnight naps that restore normal blood pressure patterns and minimize performance impairment among night shift workers. The study, conducted by the University of Pittsburgh, aims to address the disproportionate cardiovascular disease risk faced by night shift workers in public safety and...
- This federal Project Grant award, provided by the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research), supports a comprehensive sleep neuroimaging study to investigate the role of local sleep disturbance in obesity risk. The $568,125 award to Brigham Young University, with a period of performance from September 2025 to August 2028, will utilize advanced functional neuroimaging and polysomnographic methods to elucidate the underlying mechanisms linking poor...
- This $281,560 Project Grant was awarded by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research federal grant program (CFDA 93.837). The funding supports mathematical modeling research to investigate peripheral metabolic circadian rhythms and their implications for managing shift work and jet lag. The project aims to develop and validate models for peripheral circadian rhythms, which may underlie short-term gastrointestinal symptoms and longer-term...
- This federal Project Grant award, valued at $678,710 and awarded on June 15, 2025, was provided by the National Heart, Lung, and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837). The award supports the development and validation of a novel multi-sensor machine learning approach to precision sleep tracking for nightshift workers. The project aims to leverage wearable devices, environmental sensors, and machine learning algorithms to accurately detect sleep patterns...
This Project Grant award for $730,993.00 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports research to investigate the mechanisms by which internal circadian misalignment contributes to the cardiometabolic risk associated with sleep loss. The project aims to determine if preventing light exposure and food intake during the circadian biological night can mitigate the adverse cardiometabolic effects of insufficient sleep. Researchers at the University of Utah will conduct this research over the award period from Sep 1, 2025 to May 31, 2030. The findings could lead to new interventions to reduce cardiometabolic disease risk in populations prone to sleep loss, such as medical and military personnel, emergency responders, shift workers, and students.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $731.0k | 8/27/25 |