Project Grant R01HL179303
- The National Cancer Institute of the National Institutes of Health awarded the University of Southern California $426,828 on July 6, 2026, through the Cancer Cause and Prevention Research program (CFDA 93.393) to test regulatory strategies promoting e-cigarette cessation among young adults. The University of Southern California will conduct a study using a simulated vape shop experimental laboratory space ("The Puff Point") to evaluate two innovative policy interventions designed to...
- The National Heart, Lung, and Blood Institute awarded the University of Maryland, Baltimore $116,625 under Project Grant R03HL188068 on August 15, 2026, to conduct a randomized, within-subject crossover study comparing cardiovascular effects of combustible cigarette smoking and electronic cigarette use in older adults with hypertension. The study enrolls 30 participants aged 50 and older with hypertension and assigns each to two 14-day phases: continued smoking and exclusive use of an authorized...
- The National Heart, Lung, and Blood Institute awarded The Leland Stanford Junior University $718,824 in project grant funding (R01HL188006) on August 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837). The award funds research into the mechanisms by which electronic cigarette exposure drives vascular injury and atherosclerosis progression through the glutamate N-methyl-D-aspartate receptor (NMDAR) pathway in vascular smooth muscle cells. The research comprises three...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded Health Research, Inc. Roswell Park Division (doing business as Health Research At Roswell Park) $867,448 under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077) on August 1, 2026. The recipient will conduct research assessing whether use of fruit-flavored electronic nicotine delivery systems (ENDS) relates to smoking reductions in people who smoke...
- The National Heart Lung and Blood Institute awarded the Regents of the University of Michigan $234,000 on September 1, 2026, under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077, Assistance Listing 93.077) to examine how the duration of electronic nicotine delivery systems (ENDS) use affects cardiopulmonary health outcomes among adults with current or former cigarette smoking histories. The research leverages prospective, nationally...
- The National Institutes of Health National Cancer Institute awarded Cincinnati Children's Hospital Medical Center $694,182 on June 1, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct a prospective longitudinal cohort study examining biomarker levels and respiratory health effects associated with exposure to electronic cigarettes and combustible cigarettes in young children. The research enrolls 300 children ages 1 to 10 years across three equal exposure...
- The National Heart, Lung, and Blood Institute awarded The Regents of the University of California, San Francisco $127,168 on April 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to model the effect of apolipoprotein L1 risk variants on cardiovascular disease risk in African American e-cigarette users. The research employs human induced pluripotent stem-cell-derived endothelial cells to investigate how e-cigarettes, with and without menthol, affect endothelial health in...
- The National Institute on Drug Abuse awarded the Research Foundation For Mental Hygiene, Inc. (operating through its New York State Psychiatric Institute division) $195,804 on August 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279). The award funds a five-year research project examining how cannabis influences nicotine use among young and emerging adults (ages 18–35) who use electronic nicotine delivery systems. The study integrates human laboratory methods with...
- The National Institutes of Health awarded Health Research, Inc. (Roswell Park Division) $830,722 on August 15, 2026, under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077) to assess the respiratory effects of inhaling synthetic coolants used as flavor ingredients in electronic nicotine delivery systems. The project will evaluate pulmonary function and inflammatory effects resulting from inhalation of the synthetic coolants WS-3 and WS-23, which...
- The National Cancer Institute awarded the University of Southern California $733,023 on September 3, 2026, under the Cancer Cause and Prevention Research program (CFDA 93.393) to conduct randomized experiments and eye-tracking studies examining how influencer-driven e-cigarette marketing on social media affects adolescent perceptions and use patterns. The project will conduct two randomized between-subject experiments among 6,000 adolescents per experiment recruited nationwide and an...
The Department of Health and Human Services National Institutes of Health Office of the Director awarded $821,294 to The Trustees of Columbia University in the City of New York on September 1, 2026, under the Family Smoking Prevention and Tobacco Control Act Regulatory Research program (CFDA 93.077, Project Grant R01HL179303). The award funds the VAPESCAN study, a longitudinal investigation examining early lung toxicity associated with e-cigarette versus cigarette use in young adults aged 18–50. The study will re-examine 200 participants stratified into four groups: 50 e-cigarette-only users, 50 cigarette-only users, 50 dual e-cigarette and cigarette users, and 50 non-users serving as controls. The research involves deep phenotyping through 129-xenon MRI and gene expression profiling of whole blood, hair, and nasal samples; metals assessment in blood, urine, and personal e-cigarette aerosols; pulmonary function testing including spirometry and diffusing capacity measurement; urinary cotinine and tetrahydrocannabinol quantification; and comprehensive questionnaires on tobacco, e-cigarette, and other exposures. The study builds on preliminary VAPESCAN cohort findings associating e-cigarette use with lower diffusing capacity and emphysema-like computed tomography findings, aiming to elucidate mechanisms and inform tobacco regulatory science. Performance occurs at Columbia University's Health Sciences Division in New York, New York. The period of performance runs from September 1, 2026, through August 31, 2031. This is a Project Grant assistance award.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $821.3k | 9/2/26 |