Project Grant K99HL183741
- Federal Project Grant Award Summary The University of California, San Francisco (UCSF) received a $804,982 Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective July 25, 2025, with completion targeted for April 30, 2029. This award supports research investigating genetic ancestry effects on molecular and complex traits utilizing Trans-Omics for Precision Medicine (TOPMed) project data. The...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Regents of the University of California, San Francisco a project grant of $638,900 (awarded September 15, 2025, through June 30, 2030) under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct basic biomedical research investigating the role of pathologic fibroblast subsets in silicosis. The research deliverables include scientific investigations into the cellular and molecular...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the University of California, San Francisco a Project Grant totaling $709,902 under the Cardiovascular Diseases Research program (CFDA 93.837) for the Sex, HIV, and Air Pollution Effects on Post-TB Lung Disease (SHAPE PTLD) study. Initiated August 1, 2025, and extending through May 31, 2030, this research initiative aims to establish a well-characterized cohort of tuberculosis survivors with post-TB...
- Federal Project Grant Award Summary The University of California, San Francisco received a $100,998 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded August 19, 2025, with completion targeted for August 31, 2027. This research initiative will deliver a comprehensive population-based investigation evaluating the effects of universal pre-kindergarten (Pre-K) access policies on parents' cardiovascular...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded University of California, San Diego a $169,256 Project Grant on July 23, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to support research titled "Protective Poison at High Altitude: Therapeutic Effects of Elevated Endogenous CO from Adaptive HMOX2 Variants." The research project, with performance completion targeted for March 31, 2027, focuses on elucidating the...
- Federal Project Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a $568,177 Project Grant to The Regents of the University of California, San Francisco (UCSF) on August 10, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837). This award funds a research initiative investigating how centrioles—the core structural components of centrosomes—control mammalian development, with particular focus on heart, lung, and inner ear development through May...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded the Regents of the University of California, San Francisco a $556,295 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) effective August 1, 2025, with completion scheduled for May 31, 2030. This award supports research to advance understanding of cardiac pacemaking physiology and sinus node dysfunction (SND) through investigation of specialized pacemaker cell subpopulations. The...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded a $130,065 Project Grant on July 10, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to The Regents of the University of California, San Francisco. The award supports the REMOTE-BP (Research and Mentorship for Optimizing Treatment and Evaluation of Blood Pressure) initiative, which conducts systematic economic analyses of remote team-based hypertension care delivery models implemented...
- Federal Grant Award Summary The National Heart, Lung, and Blood Institute (NHLBI) awarded The Regents of the University of California, San Francisco a Project Grant of $1,097,760 under the Cardiovascular Diseases Research program (CFDA 93.837) on February 15, 2026, with performance completion targeted for December 31, 2032. This research initiative will investigate mechanisms underlying age-related pulmonary fibrosis (IPF), a progressive lung disease affecting approximately 200,000 patients...
- Federal Grant Award Summary The University of California, San Francisco (UCSF) received a $722,299 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective August 1, 2025 through July 31, 2030. This award funds a research initiative applying deep learning models to quantify aortic valve measurements in 100,000 UK Biobank participants to identify shared genetic and epidemiological factors underlying normal...
The National Heart, Lung, and Blood Institute (NHLBI) awarded $127,168 to The Regents of the University of California, San Francisco (UCSF) under the Cardiovascular Diseases Research program (CFDA 93.837) for a two-year project beginning April 1, 2026, and concluding March 31, 2028. This project grant supports research modeling the effects of apolipoprotein L1 (APOL1) genetic risk variants on cardiovascular disease (CVD) risk in African American e-cigarette users through the use of human induced pluripotent stem cell-derived endothelial cells. The research addresses a significant health disparity, as African American individuals carry APOL1 risk variants at substantially higher prevalence than other populations and face disproportionately higher risks of tobacco-related CVD. The project will deliver comparative analyses of how e-cigarettes with and without menthol affect endothelial cell health in the context of APOL1 risk variants, benchmarked against traditional cigarette effects. Research outputs will include identification of molecular markers and pathways associated with CVD susceptibility in African American tobacco product users, potentially informing future prevention and intervention strategies for this high-risk population. Performance of the research will occur at UCSF's San Francisco facility.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $127.2k | 4/1/26 |