Project Grant R01HL178400
- This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Federal Grant Program for Cardiovascular Diseases Research (CFDA 93.837), provides $123,104 to Emory University to conduct research on factors contributing to cardiovascular disease (CVD) comorbidities in persons living with HIV (PWH). The key objectives are to: 1) assess relationships between the metabolome, lipidome, HIV reservoir, and subclinical CVD, analyzing differences by sex; and 2) determine...
- This federal Project Grant award for $657,907 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support a 5-year longitudinal analysis to understand the impact of expanding pharmacists' scope of practice on the uptake and retention of pre-exposure prophylaxis (PrEP) for HIV prevention. The project aims to integrate multiple data sources, including policy, census, survey, and medical claims data, to...
- This $747,000 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) will fund research to determine the effects of pre-exposure prophylactic (PrEP) drugs on female genital HIV infection and women's reproductive health. The research will focus on understanding how PrEP impacts the female reproductive tract microenvironment and any potential...
- This federal Project Grant award of $2,981,544.00, awarded by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), will fund a study to assess the impact of asymptomatic cytomegalovirus (CMV) infection on cardiovascular event risk in people with treated HIV infection. The study will leverage data from a prior clinical trial of the CMV-specific antiviral drug letermovir and a case-cohort study of over 1,900 ART-suppressed people with HIV to...
- The National Heart, Lung, and Blood Institute (NHLBI) awarded a $774,229 Project Grant under the Cardiovascular Diseases Research (CFDA 93.837) program to Kaiser Foundation Hospitals to conduct a large longitudinal cohort study on cardiometabolic outcomes among adolescents and young adults (AYA). The goal is to better understand the epidemiology of cardiometabolic conditions like hypertension, prediabetes, and fatty liver disease in AYA populations, identify high-risk groups, and inform early...
- This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $193,754 to The Children's Hospital Corporation (dba Boston Children's Hospital) to develop an implementation strategy for pre-exposure prophylaxis (PrEP) in pediatric primary care settings. The key objectives are to: 1) explore barriers and facilitators to PrEP discussions, prescribing, and persistence among adolescents and young adults...
- This federal Project Grant award of $1,066,077 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research (CFDA 93.855) program. The grant will fund a Type 3 hybrid effectiveness-implementation study to evaluate the "PrEP & Soccer" intervention delivered through CVS pharmacy locations in Miami-Dade, Florida. The intervention aims to increase PrEP knowledge and initial PrEP appointment attendance among...
- This $798,698 project grant, awarded by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837), aims to comprehensively characterize cardiac and physical function in youth with perinatally-acquired HIV (YPNHIV) compared to HIV-unexposed (HU) and HIV-exposed uninfected (PHEU) individuals. The research will utilize cardiac imaging, physical function assessment, autonomic dysfunction analysis, and molecular profiling to elucidate determinants of...
- The National Heart Lung and Blood Institute (NHLBI) awarded a $3,264,423 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to The Regents of the University of California, San Francisco (UCSF) to study the mechanisms underlying the increased risk of sudden cardiac death in people with HIV. The research aims to characterize the myocardial tissue effects of treated HIV, including immune activation, cardiac ion channel dysregulation, and region-specific arrhythmic...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $3,554,273 to the Fred Hutchinson Cancer Center in Seattle, WA to assess the impact of oral pre-exposure prophylaxis (PrEP) on the pharmacokinetics of monoclonal antibodies and vaccine-induced antibodies among women vulnerable to HIV-1. The key objectives of this 4-year award are to: 1) Determine whether oral...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) provides $743,492 to Kaiser Foundation Hospitals to conduct a longitudinal study evaluating the effects of HIV pre-exposure prophylaxis (PrEP) on cardiovascular, kidney, and metabolic health outcomes. The study will leverage electronic health record data from integrated health systems in California and the mid-Atlantic region to examine potential cardiovascular disease risks associated with long-term use of tenofovir-based PrEP regimens, especially among diverse populations. The award period runs from September 5, 2025 through June 30, 2029, supporting research to inform clinical management and risk factor control for this expanding PrEP-using population.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $743.5k | 9/8/25 |