Project Grant R01HD122906
- The National Institute of Child Health and Human Development awarded Vanderbilt University Medical Center $785,385 on September 2, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to evaluate the safety and efficacy of glucagon-like peptide-1 receptor agonists (semaglutide, liraglutide, tirzepatide) for pre-pregnancy weight management and pregnancy outcomes. The research leverages the National Patient Centered Clinical Research Network to conduct a...
- The National Institute of Child Health and Human Development awarded Oregon Health & Science University $746,208 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate the role of the corpus luteum on placental development and adverse pregnancy outcomes in programmed frozen embryo transfers. The research will employ two novel non-human primate models to examine first-trimester corpus luteum and placental development. The project...
- The National Institute of Child Health and Human Development awarded Oregon Health & Science University $2.72 million on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate how maternal HIV infection and long-acting antiretroviral therapy affect fetal immune development using a rhesus macaque model of simian immunodeficiency virus infection. The research uses a translational animal model to distinguish the effects of HIV...
- The National Institute of Child Health and Human Development awarded Massachusetts General Hospital $672,715 on June 18, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct the Metabolic Assessment of Metformin in Pregnancy (MOM-P) study. The award funds research to assess the physiological effects of metformin on maternal and neonatal metabolism during pregnancy in individuals developing gestational diabetes mellitus. The study examines...
- The National Institute of Child Health and Human Development awarded Weill Medical College of Cornell University $727,070 on June 2, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to derive real-world insights from electronic health records and machine learning to inform clinical trials for pregnant individuals taking medications. The project addresses critical evidence gaps arising from the routine exclusion of pregnant women from clinical trials....
- The National Institute of Child Health and Human Development awarded Emory University $639,857 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865, Assistance Listing 93.HDR) to conduct longitudinal magnetic resonance imaging assessment of the maternal obesity-placenta-brain axis from gestation through infancy. The study addresses pre-pregnancy obesity affecting 29 percent of U.S. pregnant women and its impact on perinatal neurodevelopment and...
- The National Institute on Drug Abuse awarded Oregon Health & Science University $759,210 on April 1, 2026, under the Drug Use and Addiction Research Programs (CFDA 93.279) to investigate the impact of prenatal tetrahydrocannabinol (THC) exposure on offspring neurodevelopment using a translational rhesus macaque model. The award funds research to establish a direct causal association between maternal cannabis use during pregnancy and adverse offspring brain and behavioral development. The...
- Federal Grant Award Summary Oregon Health & Science University (OHSU) received a $1.49 million Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award, effective July 1, 2025, through June 30, 2028, funds research examining the mechanisms and optimization of malaria chemoprevention strategies to improve birth outcomes in Africa. The project addresses the...
- Federal Grant Award Summary Oregon Health & Science University (OHSU) received a $442,071 Project Grant (R21 mechanism) from the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded on August 18, 2025, with a completion date of July 31, 2027. This award supports research into novel therapeutic approaches for congenital hyperinsulinism (CHI), a life-threatening infantile and childhood...
- The National Institute of Child Health and Human Development awarded Cincinnati Children's Hospital Medical Center $140,072 on January 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to investigate how white adipose tissue inflammation in pregnancy affects labor timing and preterm birth risk. The research uses a mouse pregnancy model to define sources of pro-inflammatory cytokine production throughout pregnancy, with specific focus on how white...
The National Institute of Child Health and Human Development awarded Oregon Health & Science University $752,721 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct research on the impact of semaglutide on maternal-fetal health outcomes. The research uses a non-human primate model of maternal obesity to evaluate whether preconception weight loss achieved through semaglutide treatment, continued through pregnancy and weaning, is safe and effective for mothers and reduces offspring's long-term risk of obesity and obesity-related complications. The study compares this sustained-treatment approach to cessation of semaglutide upon pregnancy confirmation, which may lead to weight regain or excessive gestational weight gain. The research addresses the gap between intensive lifestyle interventions (achieving modest 4–8 percent long-term weight loss) and metabolic-bariatric surgery (20–30 percent weight loss but limited applicability) by examining glucagon-like peptide 1 receptor agonists, which achieve average weight losses of 15 percent or greater and hold potential benefit for millions of women with preconception diabetes and obesity. Performance occurs at Oregon Health & Science University's Portland, Oregon location. The period of performance runs from September 1, 2026, through June 30, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $752.7k | 9/1/26 |