Project Grant R01HD121988
- Federal Grant Award Summary The University of Kansas Center for Research Inc. received a $250,000 Project Grant award from the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR), under CFDA 93.433, effective September 1, 2025, through August 31, 2028. This three-year research project will evaluate the effectiveness of a community-based Functional Fitness (FF) intervention on functional health outcomes for adults with mobility disabilities through a...
- The National Institute on Aging awarded the University of Kansas Medical Center Research Institute, Inc. $312,736 on March 1, 2026 under the Aging Research program (CFDA 93.866) to investigate the association between body composition, physical activity, and cognitive function in adults with Down syndrome. The research examines how obesity and moderate-to-vigorous physical activity relate to cognitive outcomes in adults with Down syndrome, who face approximately a 90 percent lifetime risk for...
- The National Institute on Aging awarded The University of Texas Southwestern Medical Center $799,870 on September 1, 2026, under the Aging Research program (CFDA 93.866) to conduct a randomized controlled trial testing a multi-dimensional tailored telehealth intervention for heart failure with preserved ejection fraction in older adults. The intervention integrates physical rehabilitation targeting strength, balance, mobility, and endurance with health coaching addressing emotional regulation...
- The National Institute on Aging awarded the University of Illinois $3,781,063 on August 1, 2026, under the Aging Research program (CFDA 93.866) to adapt and test the Fit & Strong evidence-based physical activity intervention for older women living with HIV experiencing mobility decline. The funded work adapts a strength-training, balance, and behavior-change program to address HIV-specific physical, psychosocial, and contextual needs of women aged 50 years and older. The study employs a...
- The National Institute of Child Health and Human Development awarded the University of Maryland, Baltimore $433,595 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a proof-of-concept study examining whether blood flow restriction combined with low-intensity resistance training enhances force generation and motor performance in stroke survivors with upper extremity paresis. The study will enroll thirty-two participants with...
- The National Institute of Child Health and Human Development awarded the University of Alabama at Birmingham $640,699 on June 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a Phase II randomized controlled trial evaluating a telehealth-delivered extended reality exergaming intervention for children with cerebral palsy. The project, led by Byron Lai, Ph.D., addresses cardiovascular disease risk and physical deconditioning in children...
- The National Institute on Aging awarded the University of Kansas Medical Center Research Institute, Inc. $3,254,395 on July 1, 2026, under the Aging Research program (CFDA 93.866) to implement and evaluate the Brain Health Care Accelerator (BHCA), a clinical and systems intervention designed to improve Alzheimer's disease and related dementias detection in primary care. The BHCA integrates structured cognitive assessments, blood biomarkers including plasma phosphorylated tau-217, electronic...
- The National Institute on Aging awarded Healthpartners Institute $1.489 million on July 1, 2026, under the Aging Research program (CFDA 93.866) to conduct an optimization trial of MAP TO HEALTH, a digital intervention designed to increase physical activity in midlife adults. The award extends through June 30, 2031. The project develops and tests a meaning- and theory-based digital behavior change intervention that delivers personalized, timely messages reminding users of their personal reasons...
- The National Institute on Aging awarded the University of North Carolina at Chapel Hill $642,030 through the Aging Research program (CFDA 93.866) on September 1, 2026, to conduct a multi-site, blinded, randomized controlled trial evaluating a wearable ankle power training intervention with push-off biofeedback to improve gait performance and walking function in older adults. The award funds a four-year project (through August 31, 2030) examining the efficacy of smart passive ankle resistance...
- The National Institute of Child Health and Human Development awarded the University of Illinois $141,585 on January 29, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to conduct a research study examining associations among physical activity, brain vascular function, cognitive processing speed, and central nervous system neuronal integrity in persons with multiple sclerosis compared with age-, sex-, and body mass index-matched controls. The study...
The National Institute of Child Health and Human Development awarded $350,000 to the University of Kansas Center For Research Inc. on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to conduct an 18-month hybrid effectiveness-implementation randomized controlled trial examining adaptive functional fitness for adults with mobility disabilities. The study will evaluate adaptive functional fitness—a group-based, community-delivered exercise model focused on multi-joint movements mirroring activities of daily living—against a health education control across four sites among 120 community-dwelling adults with mobility disabilities. Participants randomized to the functional fitness arm will receive in-person, group-based classes delivered by certified adaptive functional fitness trainers over six months of active delivery (twice weekly), followed by six months of maintenance (once weekly) and a six-month no-contact follow-up. Control participants will receive virtual health education sessions. The primary outcome measures changes in patient-reported physical function at six months using the PROMIS Physical Function for Mobility Aid Users scale; secondary outcomes include performance-based functional assessments addressing strength, endurance, balance, and gait speed. The trial will assess sustained improvements across 12 and 18 months, analyze mediators such as session attendance, pain, and fatigue, and examine moderators including sex, age, baseline function, and ambulatory status. A mixed-methods implementation component will assess the potential for future adoption and sustainability of adaptive functional fitness. Performance occurs in Lawrence, Kansas, with the period of performance running through July 31, 2031.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $350.0k | 7/27/26 |