Project Grant RF1AG105013
- The National Institute for Minority Health and Health Disparities awarded the University of Illinois $907,321 on June 18, 2026, under the Minority Health and Health Disparities Research program (CFDA 93.307) to adapt and test the Fit & Strong! evidence-based physical activity and education intervention for older women aged 50 and older living with HIV. The award funds development of a tailored intervention that integrates group-based physical activity and behavior change strategies to...
- The National Institute on Aging awarded Northwestern University $794,664 under the Aging Research program (CFDA 93.866) on July 15, 2026, to investigate senescence-associated pathways in people living with HIV who experience premature aging. The research targets novel mechanisms of healthy aging in HIV by examining senescence-associated glycan-degrading enzymes (β-galactosidase and sialidase) that degrade anti-inflammatory glycans on circulating glycoproteins, disrupting pathways that inhibit...
- The National Institute on Aging awarded $450,928 to the University of Connecticut on June 1, 2026, under the Aging Research program (CFDA 93.866) to conduct secondary data analysis characterizing phenotypes of chronic disease among people aging with HIV in the United States. The project applies a syndemic framework to examine how multiple co-occurring health conditions cluster and interact under conditions of social and structural adversity, with the goal of identifying disease burden patterns...
- The National Institute on Aging awarded the University of Miami $783,407 on August 15, 2026, under the Aging Research program (CFDA 93.866) to conduct a randomized controlled trial of a health promotion intervention for older adults with HIV and documented cardiovascular risk. The study, titled "Strengthening Hearts and Minds: A Health Promotion Strategy for Older Adults with HIV," will enroll 180 adults age 50 and older and randomize them to either the HOPE (Happy Older People Are...
- The National Institute on Aging awarded The University of Chicago $597,239 on September 1, 2026, under the Aging Research program (CFDA 93.866) to support investigation of inpatient rehabilitation facility (IRF) utilization and outcomes for older adult patients with and without Alzheimer's disease or other dementias (ADRD). The research examines comparative value and appropriateness of care delivery across post-acute care settings, specifically comparing higher-cost IRF care—which provides acute...
- The National Institute on Aging, a component of the Department of Health and Human Services, awarded The University of Chicago $157,572 on July 1, 2026, under the Aging Research program (CFDA 93.866) to develop precision dosing models for androgen receptor signaling inhibitors in metastatic prostate cancer affecting older adults. The award funds research to validate the relationship between ARSI dose intensity and wearable sensor-derived metrics—particularly daily step counts—and their...
- The National Institute on Aging awarded the University of Washington $124,551 on July 15, 2026, under the Aging Research program (CFDA 93.866, K01 award mechanism) to conduct a five-year study examining neighborhood characteristics and frailty progression in people aging with HIV. The study uses clinical data from the Centers for AIDS Research Network of Integrated Clinical Systems (CNICS) cohort, which encompasses over 50,000 people receiving HIV care across 10 sites nationwide. The research...
- The National Institute on Aging awarded the University of Illinois $227,728 on December 10, 2025, under the Aging Research program (CFDA 93.866) to conduct research refining the measurement of purpose in life among older adults with cognitive impairment and evaluating associations between purpose in life, physical activity, and cognitive function in Alzheimer's disease and related dementias. The research addresses a gap in understanding how to motivate community-dwelling older adults with...
- The National Institute on Aging awarded the University of Miami $164,766 on September 5, 2026, under the Aging Research program (CFDA 93.866) to conduct research on T cell senescence-driven immune dysfunction in aging and HIV. The research will establish a complete T cell senescence-associated secretory phenotype (SASP) atlas using fluorescence-activated cell sorting and mass spectrometry, then evaluate plasma biomarkers of T cell senescence during physiologic aging and in people with HIV. The...
- The National Institute on Aging awarded Drexel University $1,306,728 under the Aging Research program (CFDA 93.866) on August 1, 2026, to conduct a longitudinal, multi-site study examining how individual lifestyle, social circumstances, and neighborhood-level factors influence physical functioning trajectories in older adults across population subgroups and U.S. regions. The research leverages over 30 years of longitudinal data from the Multi-Ethnic Study of Atherosclerosis (MESA) cohort and...
The National Institute on Aging awarded the University of Illinois $3,781,063 on August 1, 2026, under the Aging Research program (CFDA 93.866) to adapt and test the Fit & Strong evidence-based physical activity intervention for older women living with HIV experiencing mobility decline. The funded work adapts a strength-training, balance, and behavior-change program to address HIV-specific physical, psychosocial, and contextual needs of women aged 50 years and older. The study employs a community-engaged approach, collaborating with a Community Advisory Board of older women living with HIV to tailor the intervention using the ADAPT-I framework, integrating group-based physical activity and behavior-change strategies to foster social support and empowerment while addressing individual-, interpersonal-, and community-level implementation determinants that influence program participation and retention. The research targets a population experiencing early-onset geriatric syndromes—musculoskeletal pain, functional decline, and frailty—compounded by multimorbidity, long-term HIV treatment effects, and structural barriers to evidence-based health promotion access. Performance occurs in Chicago, Illinois with a period of performance from August 1, 2026, through July 31, 2030. This is a Project Grant, the standard assistance type for NIH research funding.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 8/26/26 | ||
| Not listed | $0 | 8/24/26 | ||
| Not listed | $3.8m | 7/23/26 |