Project Grant R01HD120540
- Federal Grant Award Summary The University of Pennsylvania received a $249,000 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded on August 1, 2025, with a completion date of July 31, 2028. This research initiative, conducted in collaboration with Dr. Yoel Sadovsky, aims to enhance understanding of common obstetric disorders through deep-phenotyping pregnancy...
- Federal Project Grant Award Summary The University of Pennsylvania received a $164,190 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective February 1, 2026, through June 30, 2027. The award supports research to investigate the role and regulation of the IC2 imprinted cluster in extravillous trophoblast (EVT) differentiation, specifically examining how the...
- Federal Grant Award Summary New York University School of Medicine received a $245,782 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective February 1, 2026, through January 31, 2029. The award funds a longitudinal research study examining how maternal immune activation (MIA) during pregnancy alters fetal and infant brain development during the critical birth...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded a $163,050 Project Grant to the University of Chicago on November 22, 2025, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award extends through June 30, 2029, and supports a research initiative titled "Leveraging Enhanced Phenotyping and Causal Inference Approaches to Investigate the Effect of Maternal Medication Exposures on Child...
- Federal Project Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded Children's Research Institute a $768,372 Project Grant on September 4, 2025, under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award funds the Tracking Adverse Prenatal Brain Stressors on Offspring Development (TABS) study, which will deliver comprehensive longitudinal research services examining the neurobiological impacts of maternal...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded the University of Illinois a $1.66 million Project Grant (CFDA 93.865: Child Health and Human Development Extramural Research) effective September 10, 2025, with a completion date of May 31, 2030. The award funds research investigating transplacental immune signaling pathways that contribute to fetal brain pathology during maternal influenza infection. The research will employ spatial...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded The Children's Hospital of Philadelphia a $160,056 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective July 1, 2025 through June 30, 2030. This research initiative focuses on quantifying transplacental antibiotic exposures in newborn infants to optimize neonatal antibiotic use and reduce toxicity risks. The project will measure...
- Federal Grant Award Summary The Children's Hospital of Philadelphia Research Institute received a $730,191 Project Grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded September 1, 2025, with a completion date of May 31, 2030. This research project examines the relationship between Medicaid enrollment during the preconception period and pregnancy...
- Federal Grant Award Summary The University of Michigan has been awarded $760,950 under the Child Health and Human Development Extramural Research program (CFDA 93.865) by the National Institute of Child Health and Human Development (NICHD), effective July 1, 2025 through June 30, 2028. This project grant supports fundamental and translational research investigating how antibody-based therapeutics can modulate G protein-coupled receptor (GPCR) signaling to address critical maternal and fetal...
- Federal Project Grant Award Summary The University of Virginia received a $124,971 Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective July 1, 2026 through June 30, 2028. This research initiative investigates how early-life systemic infection and innate immune signaling disrupt neural development and shape long-term brain outcomes. The project will define...
The National Institute of Child Health and Human Development (NICHD) awarded the University of Pennsylvania a Project Grant totaling $465,870 under the Child Health and Human Development Extramural Research program (CFDA 93.865). The award, effective June 1, 2026, through April 30, 2031, supports investigator-initiated biomedical research examining postpartum maternal immunity and viral disease resistance. The research addresses a significant gap in understanding how immune system changes following childbirth enhance maternal resilience to severe viral infection, with particular focus on the role of lactation-associated physiology and maternal caregiving behaviors in triggering protective immune mechanisms. The project will deliver fundamental scientific insights into postpartum immune dynamics through two primary research objectives. Aim 1 will characterize the breadth, kinetics, and immune determinants of protection in postpartum mothers through targeted investigations of maternal resilience mechanisms. Aim 2 will examine how maternal caregiving behaviors independently contribute to enhanced viral disease resistance, decoupling caregiving effects from lactation physiology. The anticipated research outcomes will advance knowledge of maternal physiology in the postpartum period, elucidate mechanisms underlying enhanced maternal immune response to viral challenge, and establish foundational knowledge applicable to improving women's healthcare outcomes.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $465.9k | 5/27/26 |