Project Grant R01HD119067
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $2,255,352 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to The Regents of the University of Colorado, doing business as the University of Colorado-Denver. The award, effective September 15, 2025 through May 31, 2028, will fund research to determine the cellular and molecular mechanisms involved in the transfer of inflammatory signals across...
- The National Institute of Child Health and Human Development (NICHD) awarded a $424,875 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to the University of Maryland, Baltimore (UMB) to investigate the role of placental serum amyloid A (SAA) isoforms in response to sub-chronic maternal inflammation and explore whether inhibition of the SAA2 isoform using small interfering RNA (siRNA) can alleviate preterm birth and adverse fetal outcomes. The project aims...
- The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
- This $293,550 Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is funding research to investigate the effect of inherited maternal cells on BCG-specific T cell responses in HIV-exposed and unexposed infants. The award supports a study hypothesizing that reduced transmission of maternal microchimerism in utero may be a mechanism...
- This $163,145 Project Grant awarded on August 7, 2025 by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research Program (CFDA 93.865), aims to address critical questions pertaining to impaired placentation associated with fetal growth restriction (FGR). The principal investigator, a pediatric and fetal surgeon, will use this 5-year award to develop unique cross-disciplinary skills and...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $156,080 to investigate how maternal sickness impacts caregiving behaviors and the underlying neurobiological mechanisms. The research will be conducted by New York University School of Medicine and focuses on understanding how inflammation and sickness disrupt the activity of...
- The Johns Hopkins University was awarded a $225,528 Project Grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), to investigate the mechanisms by which the maternal gut microbiome contributes to adverse fetal and perinatal outcomes during influenza A virus infection in pregnant mice. The project aims to characterize changes in the maternal gut microbiome...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $588,566 to the University of Maryland, Baltimore to conduct a cross-disciplinary study on the long-term neurodevelopmental and school readiness impacts of in-utero HIV exposure on children in Sub-Saharan Africa. The research aims to establish a core team of investigators who can...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to characterize the structural and functional brain development trajectories of offspring with and without prenatal exposure to maternal psychological distress (MPD). The $768,372 award, made on September 4, 2025, will support a longitudinal study to assess the neurodevelopmental...
- The National Institute of Child Health and Human Development (NICHD) awarded a $481,250 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Oregon Health & Science University (OHSU). The grant, awarded on September 1, 2024, will support research to investigate the mechanisms of neuroinflammation and perinatal brain injury associated with intrauterine infection by the bacteria Ureaplasma parvum. Specifically, the project aims to assess...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), is funding research to investigate how the maternal immune response to influenza virus infection during pregnancy can impact fetal brain development. The overarching goal is to identify potential therapeutic targets within the transplacental immune signaling pathways that could be leveraged to improve maternal and offspring health outcomes during seasonal influenza outbreaks. The $535,039 award to the University of Illinois will support cutting-edge spatial transcriptomic analyses to define the time-dependent phenotypic and functional shifts in immune and non-immune cells at the maternal-fetal interface during maternal respiratory influenza infection. The findings could inform the development of noninvasive antenatal therapies to mitigate fetal neuroinflammation and associated neurodevelopmental disorders. The project is set to run from September 2025 through May 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $535.0k | 9/10/25 |