Project Grant R01HD117926
- Federal Project Grant Award Summary The University of Rochester received a $149,190 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded February 1, 2026, with a completion date of January 31, 2028. The project, "Mechanisms of Sperm Dysfunction by Meiotic Drive," delivers fundamental research investigating the molecular mechanisms by which Segregation...
- Federal Grant Award Summary Albert Einstein College of Medicine received a $151,040 Project Grant award from the National Institute of Child Health and Human Development under the Child Health and Human Development Extramural Research program (CFDA 93.865) effective January 1, 2026, with a completion date of August 31, 2028. The research focuses on understanding the regulation of spermiogenesis—the process of sperm cell development and maturation—specifically investigating how the E3 ubiquitin...
- Federal Project Grant Award Summary Michigan State University received a $501,659 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded June 1, 2026, with completion scheduled for February 28, 2031. The award funds investigator-initiated research to advance understanding of the molecular mechanisms underlying mammalian sperm capacitation, specifically examining the...
- Federal Grant Award Summary Syracuse University received a $2,043,430 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) for a five-year research initiative spanning September 1, 2025, through August 31, 2029. The project will develop and apply stem cell-based modeling systems to elucidate the fundamental mechanisms governing human primordial germ cell (PGC) development. The research integrates...
- Federal Project Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded the University of Connecticut a Project Grant totaling $446,875 under the Child Health and Human Development Extramural Research program (CFDA 93.865) for fundamental research into the novel role of the corpus luteum in female reproduction. The award, effective August 20, 2025 through July 31, 2027, supports investigator-initiated research examining previously undocumented functions...
- Federal Grant Award Summary The University of Southern California received a $347,919 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective July 1, 2026, through March 31, 2031. This award funds investigator-initiated research to decipher the function of arginine/glycine (RG) motifs in Piwi-Interacting RNA (piRNA)-mediated silencing and their role in...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded Boston Children's Hospital a $1.72 million Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) on August 15, 2025, with a completion date of June 30, 2030. This award supports research into neuroendocrine computations underlying stress-induced suppression of ovulation in Drosophila melanogaster (fruit flies). The research will deliver...
- Federal Grant Award Summary The National Institute of Child Health and Human Development (NICHD) awarded The Washington University a $619,913 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) effective May 15, 2026, with a completion date of March 31, 2031. The award funds investigator-initiated research examining the regulatory mechanisms of CatSper (cation channel of sperm), a sperm-specific calcium channel critical to male fertility. The...
- Federal Project Grant Award Summary Yale University received a $248,975 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 28, 2025, with completion scheduled for July 31, 2028. This award supports basic biomedical research investigating stress response signaling as a metabolic sensor in reproduction, with research performance occurring at Yale's Pittsburgh, PA facility....
- Federal Project Grant Award Summary The University of Pennsylvania received a $247,138 project grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), effective September 1, 2025, through August 31, 2028. The award funds investigator-initiated research to examine the role of the KIF2C protein in regulating microtubule cytoskeleton dynamics during the oocyte-to-embryo transition in...
Syracuse University received a $323,643 Project Grant from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded June 1, 2026, with completion targeted for February 28, 2031. The award supports investigator-initiated research to characterize the molecular interactions between the female reproductive tract (FRT) and sperm that determine fertility outcomes. The research employs Drosophila (fruit fly) as a model system to systematically study how female-derived metabolic proteins and exosomes influence sperm function, motility, viability, and fertilization competency during sperm storage and transit. The research deliverables include: (1) systematic functional characterization of FRT metabolic proteins through knockout and knockdown studies measuring sperm function and fertility parameters; (2) high-resolution microscopic mapping of spatiotemporal associations between female proteins and sperm, including the role of FRT-derived exosomes; (3) quantitative metabolomic profiling of sperm metabolism during FRT transit and storage; and (4) mechanistic determination of how female secretory tissues and exosome biogenesis influence sperm metabolism. These research outputs are designed to advance fundamental understanding of sperm-female reproductive tract interactions and contribute to the scientific knowledge base supporting improved reproductive health outcomes.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $323.6k | 6/1/26 |