This federal Project Grant award, valued at $1,526,336.00 and awarded by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 Child Health and Human Development Extramural Research program, supports a clinical and translational research study on optimizing the use of oxytocin for labor induction. The research aims to develop a better understanding of how pregnant patients physiologically and functionally respond to exogenous oxytocin administration, with the goal of improving labor induction success and reducing maternal and fetal morbidity. The key products or services to be delivered under this award include: 1) a prospective cohort study of 605 patients undergoing labor induction to develop a prediction model for labor progression using advanced contraction measures, 2) correlation of maternal serum oxytocin concentrations with contraction parameters in a subset of 84 patients, and 3) assessment of myometrial oxytocin receptor function, expression, and localization in relation to oxytocin dosage and duration. The research will be conducted by The Washington University, a prominent private research institution located in St. Louis, Missouri.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $531.3k | 4/22/25 | ||
| Not listed | $497.5k | 8/5/24 | ||
| Not listed | $497.5k | 8/5/24 |