The University of Washington was awarded a $661,258 Project Grant by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The grant, which runs from April 15, 2025 to March 31, 2030, aims to: 1) Standardize clinical evaluation, genetic testing, and data collection from patients with stillbirth across the UW hospital network; 2) Delineate maternal-fetal interface genomic and immune signatures...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), funds the development and validation of a machine learning-based fetal monitoring system to predict and prevent fetal hypoxia. The $261,310 award will support the creation of a high-sensitivity, high-specificity predictive model using a multi-site dataset of 50,000 fetal monitoring tracings coupled with...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under CFDA Program 93.865 - Child Health and Human Development Extramural Research, will fund a computational modeling study to investigate uteroplacental hemodynamics and its implications for placental development and fetal health. The $766,982 award to Carnegie Mellon University will develop and validate a novel computational framework to simulate uteroplacental...
The University of California, San Diego (UCSD) was awarded a Cooperative Agreement totaling $1,367,400 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The 5-year project, titled "UC SAN DIEGO CENTER FOR STILLBIRTH PREVENTION: MATERNAL AND PLACENTAL DETERMINANTS OF FETAL GROWTH RESTRICTION", aims to develop a maternal serum-based test for antepartum...
The National Institute of Child Health and Human Development (NICHD) has awarded a $423,985 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to the University of Illinois to develop a novel non-invasive monitoring system for detecting placental dysfunction and associated pregnancy complications. The funding will support research to utilize extracellular vesicles (EVs) circulating in maternal blood as biomarkers, using a "target recycling...
The National Institute of Child Health and Human Development (NICHD) awarded a $1,033,334 Project Grant under CFDA 93.865 (Child Health and Human Development Extramural Research) to The Trustees of the University of Pennsylvania, doing business as Clinical Practices of the University of Pennsylvania. The goal of this 5-year project, starting on September 16, 2024, is to improve understanding of stillbirth and neonatal mortality rates in sub-Saharan Africa through the collection of new...
The National Institute of Child Health and Human Development (NICHD) awarded a $411,125 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Syracuse University to develop a microfluidic human placenta organoid model. The goal is to generate human trophoblast stem cells (HTSCs) from induced pluripotent stem cells and use them to create a placenta organoid system that can replicate early/mid-gestation placental development. The researchers will study the role of...
This federal Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) provides $442,550 to quantify altered placental microstructure and correlate microstructural changes with preeclampsia. The awardee, The Administrators of the Tulane Educational Fund (Tulane University), will develop quantitative ultrasound (QUS) methods to characterize the human placenta ex vivo and...
The National Institute of Child Health and Human Development (NICHD) awarded a $493,409 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to Oregon Health & Science University (OHSU) to investigate the role of the renin-angiotensin system (RAS) at the maternal-fetal interface. The key objectives are to determine the cell-specific contributions of the RAS protein ACE2 in the placenta and decidua, and to examine RAS gene expression, protein abundance, and...
This $1,324,642 Project Grant awarded by the National Institute of Child Health and Human Development (NICHD) under CFDA 93.865 (Child Health and Human Development Extramural Research) will fund a 1-year exploratory sequential mixed methods study on the impact of the Dobbs v. Jackson Supreme Court decision on pregnancy loss care. The study has three key aims: 1) characterize clinician attitudes, knowledge, and decision-making related to pregnancy loss care in states with new abortion...