Project Grant R01GM163190
- Federal Project Grant Award Summary The University of Chicago received a $1.97 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded September 15, 2025, with completion targeted for August 31, 2029. This award supports fundamental research on multiscale simulation of key biomolecular processes in cells, specifically focusing on biological membranes, protein-protein interactions, and...
- Federal Grant Award Summary The University of Chicago received a $150,104 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective January 18, 2026, through August 31, 2028. This award funds fundamental research investigating the emergent dynamics of actin filament branch formation and aging through a multiscale computational approach. The research focuses on understanding how ATP...
- Federal Project Grant Award Summary The University of Chicago received a $1.9 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2029. This award funds fundamental research investigating the molecular basis and regulation of myosin-10, a specialized motor protein critical to cellular transport and motility. The research integrates...
- Project Grant Award Summary The University of Chicago received a $487,525 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 1, 2026 through December 31, 2030. The award supports fundamental research to develop evolution-based understanding and design principles for protein engineering through the integration of artificial intelligence (AI) and experimental biology. The...
- Federal Grant Award Summary The University of Chicago received a $410,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 15, 2026, with a completion date of December 31, 2030. This five-year research initiative develops innovative computational and statistical methods to advance causal inference in genetics and genomics. The project deliverables include novel...
- Federal Grant Award Summary The University of Chicago received a $1,075,121 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2025, through June 30, 2030. The award supports the Biophysics (BPHYS) graduate training program, an independent interdisciplinary doctoral program that delivers advanced education and research training in molecular biophysics. The program...
- Federal Grant Award Summary The National Institute of General Medical Sciences (NIGMS) awarded the University of Chicago a $150,104 Project Grant effective March 1, 2026, through February 28, 2029, under the Biomedical Research and Research Training program (CFDA 93.859). The grant supports fundamental research investigating the molecular mechanisms underlying the functional evolution of bioluminescent proteins derived from haloalkane dehalogenases. Specifically, the research examines how new...
- Federal Project Grant Award Summary The University of Chicago received a $451,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective March 1, 2026, through February 28, 2031. This award supports the development of novel statistical methods to link genetic variants identified through Genome-Wide Association Studies (GWAS) to their underlying regulatory mechanisms and causal genes. The...
- Federal Project Grant Award Summary The University of Chicago received a $820,000 Project Grant from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2025, through April 30, 2030. This award funds a research initiative to investigate bacterial secretion systems using cryo-electron tomography (cryo-ET) and associated advanced microscopy methodologies. The project will deliver fundamental structural...
- Federal Grant Award Summary The University of Chicago received a $300,000 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective October 1, 2025, through September 30, 2027. The award funds research to develop a novel class of dynamic molecules based on intrinsically disordered proteins (IDPs) that can sense environmental cues and trigger rapid, gated cellular...
The University of Chicago received a $2.51 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded June 1, 2026, with completion targeted for May 31, 2030. This award funds research to advance Electric-Field Stimulated X-ray Crystallography (EFX), a nascent technology for observing protein dynamics at atomic resolution. The project will deliver hardware installations and testing infrastructure to generalize the EFX method, calibration systems to measure electric field forces within biological molecules, and enhanced experimental methodologies for mapping protein mechanisms with unprecedented detail. The award will also produce an open-source, end-to-end software pipeline for data reduction and analysis of EFX experiments, along with computational tools that integrate experimental results with molecular simulations to improve biological interpretation. Collectively, these hardware, software, and computational deliverables are designed to enable the broader scientific community to access and practically employ EFX as a general analytical tool for understanding protein and complex biological macromolecule function, supporting fundamental biomedical research objectives aligned with NIGMS's mission to advance understanding of biological processes and disease.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.5m | 5/7/26 |