Project Grant R01GM160726
- The Massachusetts Institute of Technology (MIT) has been awarded a 5-year, $487,873 National Science Foundation (NSF) Engineering Program (CFDA 47.041) Project Grant to develop advanced label-free microscopy technologies for deep-tissue biological imaging. The project aims to create innovative fiber optic light sources, excitation methods, and algorithmic reconstruction techniques to enable label-free multiplex imaging that can visualize dynamic cellular processes within living tissue with...
- The National Institute of General Medical Sciences (NIGMS) awarded a Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the Massachusetts Institute of Technology (MIT) for $351,010. The grant, with a period of performance from January 1, 2025 to November 30, 2029, focuses on the rational design, synthesis, and characterization of cationic carbone-boracycles as far-red and near-infrared photoactive agents for applications in bioimaging and cancer therapy....
- This Project Grant award of $540,000 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to expand the MicroTutor online platform for microscopy and bioimage analysis education. The primary awardee, President and Fellows of Harvard College, doing business as Harvard Medical School, will add new modules on microscopy best practices and bioimage analysis using open-source tools like Piximi. This will...
- The National Science Foundation Division of Industrial Innovation awarded a $500,000 Project Grant to the Massachusetts Institute of Technology from August 1, 2021 to July 31, 2024. The grant supports the development of a high-performance, low-cost chip-scale platform for medical imaging under the NSF Engineering program (CFDA 47.041). MIT will leverage the funding to create a new medical imaging technology that integrates photonics, microfluidics, and electronics onto a single silicon chip. The...
- This $1,977,264 federal Project Grant, awarded by the U.S. Department of Health and Human Services' National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to develop a novel multimodal imaging platform that combines fluorescence super-resolution and tomographic polarized light imaging. The project will create open-source computational imaging tools to recover the dielectric tensor in multiple scattering samples using...
- This Project Grant award, valued at $2,977,640.00, was provided by the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to the Massachusetts Institute of Technology (MIT) with a project period from September 1, 2024 to August 31, 2027. The award will fund the development of an "Autonomous Quantum Microscope" to enable the precise positioning of atoms within a crystal lattice, allowing for the engineering of identical quantum defects. This technology aims to advance...
- This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $325,000.00 to the Massachusetts Institute of Technology (MIT) to develop 3D-integrated micro-photometer chips for monitoring neural dynamics in the brain. The project aims to elucidate the effects of beam collimation, compact chip size, and mechanical flexibility of implantable optoelectronic probes on the quality of in vivo deep-brain fluorescence recordings. The research team plans...
- This federal Project Grant award of $349,280 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of advanced machine learning algorithms for ultra-high-density, ultra-high-precision single molecule localization microscopy (SMLM). The grant recipient, Xgenomes Corp., will create a SMLM video simulator to generate training data (Aim 1), build a machine learning-based grouping...
- This $600,000 Project Grant award from the National Science Foundation's Division of Information and Intelligent Systems (CFDA #47.070 - Computer and Information Science and Engineering) supports the Massachusetts Institute of Technology (MIT) in developing a cyber physical system to remotely control cellular processes and create synthetic pancreatic tissue. The research aims to overcome challenges in recreating complex 3D tissue structures by using swarms of microrobots to regulate the...
- This $1,926,960 Project Grant was awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to Trustees of Boston University on September 15, 2025. The grant aims to develop new algorithms, engineer speckle illumination, and integrate these technologies into microscopes that enable high-speed, multicolor, and volumetric (multiplane) superresolution imaging using standard fluorescent molecules. The goal is to...
This Project Grant award, valued at $1,963,850.00 and awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of a novel "Differentiable Microscopy" technology at the Massachusetts Institute of Technology (MIT). The project aims to create a high-throughput, end-to-end imaging cytometry system by leveraging customizable nano-optics and machine learning techniques. The goal is to enable faster and more efficient acquisition and processing of cellular or tissue images for various biomedical applications, such as rare cell detection and drug screening. The award, with a performance period from August 15, 2025 to July 31, 2029, will fund MIT's research and development efforts to advance this innovative microscopy technology.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.0m | 8/6/25 |