Project Grant 2339338

Award Date 4/1/24
Completion Date 3/31/29
Dollars Obligated $488K
Federal Grant Program
47.041
Assistance Type
Project Grant
Place of Performance
Cambridge, MA 02139, USA
Similar Awards
The National Science Foundation Division of Industrial Innovation awarded a $500,000 Project Grant to the Massachusetts Institute of Technology from August 1, 2021 to July 31, 2024. The grant supports the development of a high-performance, low-cost chip-scale platform for medical imaging under the NSF Engineering program (CFDA 47.041). MIT will leverage the funding to create a new medical imaging technology that integrates photonics, microfluidics, and electronics onto a single silicon chip. The...
The Massachusetts Institute of Technology (MIT) received a $420,061 Project Grant award from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems on August 1, 2021 to develop nanosensor chemical cytometry (NCC) technologies in support of cellular therapeutics through July 31, 2024. The NSF award supports MIT's work under the Engineering (47.041) federal grant program, which seeks to foster innovation and excellence in engineering...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $305,000 to Nanores LLC aims to develop a compact, multi-color super-resolution imaging system capable of visualizing molecular structures in thick biological tissues with nanoscale precision. The key products to be delivered include: An advanced fluorescence imaging system incorporating adaptive optics and spinning disk technology to enable 3D imaging of biological samples up...
The Massachusetts Institute of Technology (MIT) received a $500,000 Project Grant award from the National Science Foundation Division of Industrial Innovation to develop a new patterning system for accelerated microchip design and manufacturing. Funded through the NSF Engineering program (CFDA 47.041), MIT aims to introduce an advanced manufacturing technology enabling flexible and rapid microchip patterning with high throughput. Specifically, the project focuses on engineering reconfigurable...
This $300,000 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports the development of a new optical microscopy technology called "Space-Time-Pulsed Engineered-Excitation for Diffraction-Free Imaging (SPEEDI)." The technology utilizes exotic space-time wave packets to enable high-resolution fluorescence imaging of deep brain tissue without the light scrambling issues of conventional microscopy. The research aims to advance imaging...
This Project Grant award, valued at $555,000.00 and awarded by the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program, supports research at the Massachusetts Institute of Technology (MIT) focused on developing advanced hybrid J-aggregate nanostructures. The primary objectives are to: Investigate how silica matrices influence the brightness, stability, and excitonic behavior of J-aggregate fluorophores, and explore solvent tunability through surface...
The National Science Foundation (NSF) awarded a Project Grant under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) to Lensguide Imaging Technology Inc. for $275,000 to develop a nano-optical imaging microendoscope for in vivo imaging. The project aims to create a hair-sized, 100 μm diameter microendoscope that can image at depths greater than 3 mm in live animals with subcellular resolution, overcoming limitations of current optical imaging technologies. This...
This Project Grant award, valued at $2,977,640.00, was provided by the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to the Massachusetts Institute of Technology (MIT) with a project period from September 1, 2024 to August 31, 2027. The award will fund the development of an "Autonomous Quantum Microscope" to enable the precise positioning of atoms within a crystal lattice, allowing for the engineering of identical quantum defects. This technology aims to advance...
The Massachusetts Institute of Technology (MIT) has been awarded a $268,162 Project Grant from the Air Force Research Laboratory under the Air Force Defense Research Sciences Program (CFDA 12.800). The grant, awarded on February 1, 2024, will fund the development of a fluorescence microscope system to enable time-lapse tracking of compact, multistable gene circuits for cellular regeneration research. This fundamental research aims to advance scientific knowledge and develop new capabilities in...
The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $300,000 EAGER (Early-Concept Grants for Exploratory Research) project grant to The Research Foundation for The State University of New York (RF SUNY) to establish near-ultraviolet (NUV) coherent anti-Stokes Raman scattering (CARS) microscopy for highly sensitive imaging of native biomolecules. This technology will be applied to develop label-free digital pathology for brain...

The Massachusetts Institute of Technology (MIT) has been awarded a 5-year, $487,873 National Science Foundation (NSF) Engineering Program (CFDA 47.041) Project Grant to develop advanced label-free microscopy technologies for deep-tissue biological imaging. The project aims to create innovative fiber optic light sources, excitation methods, and algorithmic reconstruction techniques to enable label-free multiplex imaging that can visualize dynamic cellular processes within living tissue with high molecular sensitivity and specificity. Key deliverables include new ultrabroadband fiber optic light sources tailored for deep-tissue label-free imaging, as well as optimized excitation and computational reconstruction approaches to enable high-throughput hyperspectral label-free imaging. This work has the potential to enable transformative capabilities for disease diagnosis and therapeutic monitoring while minimizing biological perturbation. The project will also leverage existing MIT outreach programs to engage K-12 students in STEM education through the development of LEGO-based microscope modules.

Generated 10/29/24, 3:27 AM