The National Institute of General Medical Sciences (NIGMS) awarded a $350,000 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Fluidispec LLC in Philadelphia, PA. The grant supports the development of a new microfluidic/nanofluidic sample preparation platform to enable enhanced low-input and single-cell proteomics analyses. The platform aims to improve protein extraction, purification, and denaturation to overcome longstanding challenges in top-down and bottom-up proteomics workflows. The funded research includes fundamental studies on the protein purification process and the anticipated performance improvements in proteome coverage and speed of single-cell proteomics. If successful, the project will provide a widely accessible system to advance low-input and single-cell proteomics capabilities.
Generated 3/4/25, 7:17 AM