Project Grant 2204681
- The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded $800,000 under the Engineering (47.041) federal grant program to develop a novel biosynthetic toolkit for rapid detection and monitoring of COVID-19 antibodies. Funded from August 1, 2022 through July 31, 2025, Indiana University will construct SARS-CoV-2 epitope peptides fused with a nanotag transducer peptide and displayed on an RNA phage platform. This biosynthetic display aims...
- This $495,516 project grant awarded by the National Science Foundation's Engineering program (CFDA 47.041) aims to develop a next-generation, ultrasensitive, and easy-to-use diagnostic platform for detecting nucleic acids. The project merges advances in nanomaterials, sensor engineering, and gene-editing-inspired detection to enable accurate and rapid identification of nucleic acids without the need for complex laboratory procedures. Key innovations include signal amplification through...
- This $447,747 Project Grant award from the National Science Foundation (NSF) Engineering Program (CFDA 47.041) to Trustees of Boston University will develop a novel plasmonic nanosensor system to detect two important classes of RNA molecules - microRNA (miRNA) biomarkers and SARS-CoV-2 viral RNA. The sensor platform uses DNA structures with nanoparticle probes that undergo conformational changes when binding to target RNAs, altering the plasmonic coupling signal which is detected via two-color...
- The Ohio State University received a $249,999 Project Grant award from the National Science Foundation Division of Industrial Innovation on June 15, 2021 to develop DNA sensors for rapid detection of COVID-19 and other viral diseases. Funded under the NSF Engineering program (CFDA 47.041), this award will support The Ohio State University Office of Sponsored Programs in engineering research to improve viral detection technologies. Specifically, the University will work to create novel DNA...
- The National Science Foundation (NSF), under its Engineering program (CFDA 47.041), awarded a $429,832 Project Grant to the University of Massachusetts (UMass) to develop a novel method for rapid and sensitive detection of nucleic acids such as DNA and RNA. The main objectives of the 5-year project are to: Determine the nanomechanoelectrical transduction principle of nucleic-acid nanostructures tethered to a graphene transistor and oscillating in an electric field. Achieve rapid,...
- This $851,000 National Science Foundation project grant supports research and educational activities under the Mathematical and Physical Sciences program (CFDA 47.049) from February 2022 through January 2027. Frederique Deiss of Indiana University-Purdue University Indianapolis will study redox reactions and single particle detection using electrochemiluminescence and microfluidics. The research aims to develop single-entity electrochemistry methods using electrochemiluminescence in droplets...
- The National Science Foundation (NSF) Engineering program (CFDA 47.041) has awarded a $550,000 project grant to the University of California, Berkeley to develop a miniaturized, sensitive, and user-friendly biosensing platform for rapid bacterial infection diagnostics. The award, effective April 1, 2025 through March 31, 2030, aims to create an integrated circuit (IC) chip and microfluidic system that combines physics-based dielectric spectroscopy and biochemistry-based magnetic nanoparticle...
- The National Science Foundation (NSF) awarded a $450,000 Project Grant under CFDA 47.041 Engineering to North Carolina State University for a 3-year period from March 1, 2025 to February 29, 2028. The project, titled "BIOCENSORS: PARSING OUT THE GENETIC PAYLOAD OF VIRUSES BY DIFFERENTIAL BIORECOGNITION OF CAPSID FEATURES", aims to develop a biosensing technology to detect defective viral particles in gene therapy applications. The project has three key objectives: 1) studying ligand...
- This $402,222 National Science Foundation Project Grant, funded through the Engineering program (CFDA 47.041), supports the development of a new class of simple, inexpensive, portable, and rapid molecular diagnostic platforms. The awardee, University of Cincinnati, will engineer an instrument that can reliably and quickly detect infectious diseases in human samples using a combination of biochemistry, magnetism, fluid physics, and machine learning insights. Specifically, the university will...
- This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $442,106.00 to Florida International University (FIU) to develop a new sensing mechanism and approach for a nanopore sensor that will enable ultrasensitive and selective detection of various small molecules under physiological conditions. The project aims to create a portable, inexpensive, and easy-to-use sensor applicable to areas such as protein analysis, pharmaceutical research,...
The National Science Foundation awarded a $793,276 Project Grant to Indiana University under the Engineering (47.041) federal grant program. The grant will fund the development of next-generation plasmonic nanosensors for ultrasensitive, high-throughput nucleic acid and protein assays from July 1, 2022 to June 30, 2025. Indiana University will construct optical-based biossensors using localized surface plasmon resonance-active metal nanostructures functionalized with photoreversible molecules. The sensors aim to assay different classes of disease biomarkers like nucleic acids and proteins from blood and urine samples. This will enable early-stage detection of diseases such as COVID-19 and cancer. The university also plans to integrate the biosensing approach into a multi-well plate format for high-throughput analysis of patient samples using a standard plate reader. The project seeks to improve clinical disease diagnosis through shorter assay times and analysis of multiple biomarkers simultaneously.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $396.6k | 6/24/22 |