Project Grant R01GM157608
Award Date
9/1/24
Completion Date
8/31/28
Dollars Obligated
$295K
Federal Agency
National Institute of General Medical Sciences
Federal Grant Program
93.859
Assistance Type
Project Grant
Place of Performance
Richardson, TX 75080, USA
Similar Awards
The National Institute of General Medical Sciences (NIGMS) awarded a $427,571 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The Regents of the University of Colorado, doing business as the University of Colorado-Denver. The award, which runs from January 15, 2025 to December 31, 2029, will support research to uncover the molecular determinants of cellular identity and the regulation of chromatin states across the cell cycle. Specifically, the...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $585,000 in funding to the University of Texas at Dallas (UTD) for the period of August 1, 2025 to May 31, 2030. The grant supports two key objectives: Developing innovative strategies and platforms for discovering 'natural product'-like macrocyclic peptides as potent and selective modulators of biomolecular interactions. This...
The National Institute of General Medical Sciences (NIGMS) awarded a $460,413 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to the University of Texas at Dallas (UTD) on April 22, 2025. The goal of this 4.7-year project is to develop a novel visible light-induced transition metal-radical hybrid catalytic methodology for regiocontrolled, mild, and exogenous oxidant-free functionalization of saturated organic groups. This research aims to create a new synthetic platform...
The National Institute of General Medical Sciences (NIGMS) awarded a $298,530 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Epigenter, LLC in Providence, RI. The goal of this 1-year award, effective July 1, 2025, is to develop and characterize "self-delivering" epigenetic editor proteins that can modulate gene expression by targeted DNA demethylation, without requiring genetic transduction. The project will compare two different protein...
The National Institute of General Medical Sciences (NIGMS) awarded a $1,335,099 Project Grant under the Biomedical Research and Research Training (CFDA 93.859) federal grant program to the University of Chicago. The 5-year award, effective September 2, 2024, will support research to identify the genetic instructions and processes that regulate long-distance interactions between enhancers and promoters, which are critical for gene expression control and have implications for human health. The...
The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training federal grant program (CFDA 93.859), awarded a $675,898 Project Grant to The University of Texas Southwestern Medical Center (UT Southwestern) to conduct research on defining the modular architecture of protein intrinsically disordered regions (IDRs) for a predictive understanding of biological function. The 5-year grant, starting on Sep 1, 2024, will use computational approaches, in...
The National Institute of General Medical Sciences (NIGMS) awarded a $406,250 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to The Trustees of the University of Pennsylvania, doing business as Clinical Practices of the University of Pennsylvania, with a performance period from January 22, 2025 to December 31, 2029. The grant aims to develop new chemistries and engineering approaches to manipulate the dynamic nascent extracellular matrix within complex...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training Program (CFDA 93.859) totals $408,750 and is effective from September 15, 2024 through July 31, 2029. The award will support the development of large-scale composite hypothesis testing approaches for performing translational genetics analyses. Specifically, the research will focus on creating interpretable and robust statistical methods for...
This $1,737,000 Project Grant awarded by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development of innovative single-cell genomics technologies for joint analysis of regulatory dynamics and transcriptional states. Key objectives include: Developing multiomics tools to measure rates of epigenomic changes (DNA methylation, demethylation, oxidative damage, DNA repair) and relate these to...
The National Institute of General Medical Sciences (NIGMS) awarded a $1,215,000 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to The University of Texas M.D. Anderson Cancer Center. The grant, effective September 1, 2024 through July 31, 2029, will support a functional analysis of arginine methylation, a common post-translational modification. The research aims to broadly understand the biological roles of arginine methylation, identify novel effector proteins that...