Project Grant R01GM155740
Award Date 9/1/25
Completion Date 8/31/29
Dollars Obligated $1.2M
Funding Federal Agency
Awarding Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Montana, USA
Similar Awards
- The federal Project Grant award of $186,354 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), is being used to conduct research on the roles of protein glycosylation in prokaryotes. The project aims to perform quantitative glycoproteomic analyses of the opportunistic bacterial pathogen Pseudomonas aeruginosa during different stages of biofilm formation and in response to antibiotics. Additionally, the...
- This federal Project Grant award of $348,963.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The award supports fundamental scientific research to investigate the mechanisms of quorum signal synthesis in gram-negative bacteria, with the goal of establishing molecular determinants for substrate recognition and developing quorum sensing inhibitors as potential anti-virulence compounds. The...
- This Project Grant award, valued at $160,040.00, was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855). The grant supports research conducted by the University of California, San Francisco (UCSF) to investigate how the bacterial pathogen Pseudomonas aeruginosa senses and responds to mechanical deformation of its cell envelope when contacting surfaces. The research aims to further...
- This federal Project Grant award for $543,750.00, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), will support research to determine the structural basis by which a C-terminal processing protease activates cell surface signaling for iron import in gram-negative bacteria. The research, to be conducted at North Dakota State University, aims to better understand essential cellular processes in...
- This federal Project Grant award of $2,233,277.00 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research to elucidate the catalytic mechanisms and regulatory roles of bacterial alarmone hydrolases. The University of Texas Southwestern Medical Center, the awardee, will use structural biology, biochemistry, and bacterial genetics to study how these enzymes, which degrade the signaling molecule...
- This Project Grant, valued at $868,776.00 and awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research federal grant program (CFDA 93.855), supports research to characterize a novel post-transcriptional regulator in the opportunistic pathogen Pseudomonas aeruginosa. The key objectives are to identify the direct regulatory targets of this regulator, called PhAF, under standard laboratory conditions and in clinically relevant...
- This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under CFDA 93.859 Biomedical Research and Research Training program, provides $361,297 to the University of Georgia Research Foundation to characterize the regulation of cell envelope biosynthesis in the bacterial pathogen Pseudomonas aeruginosa. The project aims to: (I) dissect the molecular basis of lipopolysaccharide (LPS) and peptidoglycan (PG) coordination and the physiological consequences of...
- This $137,000 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research to understand the epigenetic mechanisms underlying the heat shock response in bacteria. The award aims to investigate how exposure to heat stress leaves an imprint on bacterial cells that improves their ability to respond to future heat challenges, as well as how this memory impacts antibiotic sensitivity....
- This $540,818 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research at Columbia University on the interdependency of chemical, structural, and physiological heterogeneity in Pseudomonas aeruginosa biofilms. The project aims to investigate how biofilm and infection-site conditions impact P. aeruginosa's use of lactate as a carbon source, and how the bacteria tolerate...
- The federal Project Grant award of $189,150 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research Program (CFDA 93.855) supports research to elucidate the molecular mechanisms of the Streptococcus pneumoniae enzyme HtrA and its target interactions. The project aims to investigate the unique structural and functional features of this first family member from the largely unexplored phylogenetic branch of pathogenic Gram-positive...