Project Grant R01GM154669
Award Date
9/1/24
Completion Date
6/30/28
Dollars Obligated
$659K
Federal Agency
National Institute of General Medical Sciences
Federal Grant Program
93.859
Assistance Type
Project Grant
Place of Performance
New York, USA
Similar Awards
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), will fund research to characterize the molecular mechanisms and evolution of cyclic diguanylic acid (c-di-GMP) signaling in the antibiotic-producing bacterial genus Streptomyces. The $383,746 award, with a performance period from January 1, 2025 to December 31, 2029, will be executed by Cornell University's Office of Sponsored...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $305,208 to Cornell University to conduct research on the ubiquitin mechanism in normal cell physiology and pathogen-host interactions. The research aims to elucidate the molecular mechanisms of adaptor-mediated ubiquitination by NEDD4 family E3 ligases, as well as investigate how the intracellular bacterial pathogen Legionella...
The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $321,484 Project Grant to the University of Texas at Austin. The grant, effective May 1, 2025 through April 30, 2030, will support research to uncover the fundamental role of extracellular electron transfer (EET) in human health and apply this knowledge to develop new therapeutics and biological catalysts. Key objectives include engineering electron...
Cornell University was awarded a $1,000,000 project grant from the National Science Foundation Division of Molecular and Cellular Biosciences to support research titled "Engineering Photosensory Proteins Through the Better Understanding and Control of Proton-Coupled Electron Transfer Reactions." The award period is from August 1, 2021 through July 31, 2025. The grant funding will support basic research conducted under the Biological Sciences program (CFDA 47.074) to advance...
The National Institute of General Medical Sciences (NIGMS) awarded a $715,109 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of Illinois to uncover novel heme chemistry in microbial systems. The research aims to establish how divergent bacterial diheme proteins stabilize high-valent bis-FeIV states and utilize these intermediates for site-specific substrate oxidation. Key objectives include addressing outstanding questions related to the...
The National Institute of General Medical Sciences (NIGMS) awarded a $627,797 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Cornell University, effective May 1, 2025 through April 30, 2030. The goal of this research program is to delineate the inner workings of membrane-associated protein complexes that shape the form and function of tissues, and whose dysfunction leads to serious human diseases. The research leverages a multi-disciplinary approach...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) provides $397,022 to Cornell University to establish culture conditions for uncultured microbes. The project aims to unlock the study and utilization of uncultured microbes, with a focus on establishing the first axenic culture of the intracellular bacteria Wolbachia and using a "many-by-many" strategy to simultaneously grow a wide...
This $375,000 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports the development of redox-based bioelectronics through the Semisynbio-III award to the University of Maryland, College Park. The three-year project will advance four technological areas to create communicating microbial cells and decision-making cells that can be instructed by electric inputs to perform logic operations by writing to genomes or adjusting consortium populations....
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $393,718.00 to the Massachusetts Institute of Technology (MIT) for a research project spanning from April 11, 2025 to February 28, 2030. The project aims to study the biogeography and combinatorial effects of microbial and plant-derived redox-active small molecules on microbial growth and community dynamics in soil...
This National Science Foundation (NSF) Project Grant award under the Biological Sciences program (CFDA 47.074) provides $429,656.00 to Cornell University to conduct research using synthetic biology methods to engineer microorganisms to produce valuable plant natural products. The key objectives are to reconstitute plant biosynthetic machinery in yeast in order to better understand and harness plant enzyme complexes for natural product synthesis. This research aims to develop a more resilient...