Project Grant R01EY038692
Award Date 7/1/26
Completion Date 2/28/31
Dollars Obligated $759K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Salt Lake City, UT 84113, USA
Similar Awards
- The National Eye Institute, part of the National Institutes of Health, awarded the University of New Mexico Health Sciences Center $350,000 on September 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate neutrophil extracellular traps and chemokine signaling in blood-retinal barrier disruption in diabetic retinopathy. The funded research targets mechanisms underlying diabetic retinopathy, the leading cause of vision loss in middle-aged adults....
- The National Eye Institute awarded the University of Utah $620,926 on September 1, 2026, under the Vision Research program (CFDA 93.867) to develop an engineered human cornea chip for studying keratoconus pathology. The project investigates curvature-dependent cellular responses in corneal epithelial, stromal, and endothelial cells using a microfabricated organ chip platform. Work focuses on three specific aims: identifying mechanotransduction pathways and validating therapeutic targets...
- The National Eye Institute awarded The Leland Stanford Junior University $3,573,304 under the Vision Research program (CFDA 93.867) on September 15, 2025, to apply the TEMPO proteomic platform using human liquid biopsy samples to identify protein biomarker signatures and cells driving diabetic retinopathy stages and diabetic macular edema in living patients, and to determine the role of accelerated molecular aging in diabetic retinopathy using a proteomic clock. The TEMPO method integrates...
- The National Eye Institute awarded The Schepens Eye Research Institute $858,394 on August 1, 2026, under the Vision Research program (CFDA 93.867) to develop multimodal foundation models for eye disease screening and prognosis. The research develops a vision-language foundation model trained on pairs of retinal images and clinical notes to enable downstream supervised models for detection and progression prediction of age-related macular degeneration, diabetic retinopathy, and glaucoma. The...
- The National Eye Institute awarded the University of California, Los Angeles $722,904 on May 1, 2026, under the Vision Research program (CFDA 93.867) to conduct secondary analysis of optical coherence tomography (OCT) imaging and clinical data from four NEI-funded uveitis randomized clinical trials, investigating OCT biomarkers—including ellipsoid zone integrity, photoreceptor layer thickness, intraretinal hyperreflective foci, choroidal thickness, and disorganization of retinal inner...
- The National Eye Institute awarded The University of Iowa $440,263 on May 1, 2026, under the Vision Research program (CFDA 93.867) to investigate osmotic regulation in cone dystrophy with supernormal rod response (CDSRR), a rare inherited retinal disease causing progressive vision loss beginning in early childhood. The project uses state-of-the-art imaging biomarkers and transcriptomics to evaluate osmotic regulation in mouse models of CDSRR, a disease caused by mutations in the KV2.1/KV8.2...
- The National Eye Institute awarded the University of California, Davis $287,457 on July 1, 2026, under the Vision Research program (CFDA 93.867) to develop and validate machine learning models predicting treatment response, disease activity, and complications risk in patients with non-infectious uveitis. The recipient will extract detailed ocular examination data from electronic health records and build predictive tools for integration into clinical workflows, providing clinicians with real-time...
- The National Eye Institute awarded The Regents of the University of California, San Francisco $984,000 under the Vision Research program (CFDA 93.867) on September 30, 2025, for planning and feasibility research on a decentralized clinical trial design for dry eye disease. The recipient will develop a remote trial methodology that shifts dry eye disease study away from clinical settings into participants' home environments, addressing limitations in traditional randomized clinical trials...
- Federal Grant Award Summary The National Eye Institute (NEI), under the Vision Research program (CFDA 93.867), awarded $830,024 to The Regents of The University of Colorado-Denver for a two-year project (September 1, 2025 – August 31, 2027) titled "Elucidating Competence and Fate Choice Dynamics During Retinal Development." The project aims to advance understanding of retinal cell development mechanisms by investigating how Notch signaling regulates cell fate decisions in the...
- The National Eye Institute awarded the University of Rochester $684,914 on July 1, 2026, under the Vision Research program (CFDA 93.867) to develop human induced pluripotent stem cell (hiPSC)-derived retinal tissue models for disease research and cell-based therapeutic applications. The award funds two complementary aims. Aim 1 develops a microphysiological model of comprehensive hiPSC-derived retina that emulates the physiological spherical geometry of the human retina in vivo, suitable for...