Project Grant R01EY036943
Award Date 9/1/25
Completion Date 5/31/28
Dollars Obligated $503K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
California, USA
Similar Awards
- The National Eye Institute (NEI), under the Department of Health and Human Services, has awarded a $695,050 Project Grant to The Leland Stanford Junior University (Stanford University) to investigate the role of cholinergic dysfunction in the pathogenesis of glaucoma. The grant, funded through the NEI's Vision Research program (CFDA 93.867), aims to leverage advanced magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques to identify and quantify cholinergic changes in the visual...
- The National Eye Institute (NEI) awarded a $451,000 Project Grant under the Vision Research federal grant program (CFDA 93.867) to The Regents of the University of California, San Francisco (UCSF) to conduct a multimodal characterization of a novel inherited mouse model of glaucoma. The research aims to evaluate structural and functional changes in the mouse model, including axonal degeneration, retinal ganglion cell loss, dendritic changes, and neuroinflammatory responses. It will also identify...
- The U.S. National Eye Institute (NEI) awarded a Project Grant under the Vision Research federal grant program (CFDA 93.867) to The Leland Stanford Junior University (Stanford University) in the amount of $257,785. The grant supports research to investigate the role of DNA damage response pathways, specifically the inhibition of checkpoint kinase 1 (CHK1), in enhancing retinal ganglion cell survival and promoting neuroprotection for the treatment of traumatic optic neuropathy (TON). The...
- This Project Grant award from the National Eye Institute (NEI), under the federal Vision Research program (CFDA 93.867), provides $247,387 to Stanford University to establish a comprehensive strategy for recruiting, training, and retaining clinician-scientists in ophthalmology research. The overarching objectives are to educate and develop the next generation of clinician-scientists focused on vision-related diseases and disorders, and to enhance research capabilities within ophthalmology...
- This federal Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides $654,455 to The Leland Stanford Junior University to develop fair and generalizable artificial intelligence (AI) algorithms for predicting glaucoma progression. The goal is to address racial/ethnic disparities in the performance of these AI models, which disproportionately impact minority populations. The research involves comparing fairness-aware algorithm training methods, evaluating model...
- This federal Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) provides $357,056 to The Leland Stanford Junior University to conduct research on retinal circuit integration and degeneration in neurofibromatosis type-1 (NF1). The key objectives are to: 1) Evaluate the functional impact of retinal ganglion cell (RGC) loss during NF1 progression and the effects of RGC transplantation on the remaining retinal circuitry, and 2) Examine if transplanted RGCs can form...
- The U.S. National Eye Institute awarded a $1,397,496 Project Grant under its Vision Research federal grant program (CFDA 93.867) to The Leland Stanford Junior University. The grant, with an award date of August 1, 2025 and an ultimate completion date of March 31, 2030, will support research to identify the mechanism underlying the interplay between the loss of the ARMC9 gene and impaired mitochondrial function in the formation of cilia in Joubert Syndrome, a rare inherited form of retinal...
- This Project Grant award from the National Eye Institute (CFDA 93.867 Vision Research) provides $127,861 to The Regents of the University of California, Berkeley to conduct research on the role and regulation of a distinct optic nerve microglia population in glaucomatous neuropathy. The research aims to elucidate how the lipoxin LXB4 regulates disease-associated microglia (DAM) in the optic nerve during ocular hypertension, a key mechanism in the neuroprotective effects of LXB4 against...
- This Project Grant award of $568,122.00, provided by the National Eye Institute (CFDA 93.867 - Vision Research), supports research at Baylor College of Medicine to unequivocally confirm the contribution of the neurovascular unit to glaucoma pathogenesis and identify endothelial cell-specific ligands with potential for neuroprotective therapy. The research aims to globally map ligands binding to ocular hypertension and healthy retinal cells, systematically identifying ocular...
- This $417,162 Project Grant award from the National Eye Institute (CFDA 93.867 - Vision Research) supports research on using optical techniques to detect early signs of glaucoma, the leading cause of irreversible blindness worldwide. The University of Houston System, the grantee, will conduct research to determine if changes in the birefringence (optical properties) of the lamina cribrosa and posterior eye structures can serve as sensitive early indicators of glaucoma before structural damage...
This federal Project Grant award from the National Eye Institute (NEI), under the Vision Research federal grant program (CFDA 93.867), provides $502,677 to The Leland Stanford Junior University (Stanford University) to develop chemical modulators of endoplasmic reticulum (ER) stress as neuroprotective treatments for glaucoma. The research aims to optimize promising ER stress modulator compounds identified through high-throughput screening, evaluate their efficacy in mouse models of glaucoma, and elucidate their mechanisms of action. The project runs from Sep 1, 2025 to May 31, 2028, with the goal of identifying preclinical drug candidates and establishing translational strategies for the clinical management of glaucoma patients.
Generated 10/21/25, 6:22 AM
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $502.7k | 8/15/25 |