Project Grant R01ES038122
- The National Institute of Environmental Health Sciences awarded the University of Massachusetts $752,690 on August 13, 2026, for research on preconception and early pregnancy exposure to endocrine-disrupting chemicals under the Environmental Health grant program (CFDA 93.113). The project investigates how exposure to perfluoroalkyl and polyfluoroalkyl substances (PFAS), polybrominated diphenyl ethers (PBDEs), and trace elements affects women's reproductive health and the ability to achieve...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Massachusetts Lowell $157,437 under the Environmental Health program (CFDA 93.113) on May 10, 2025, for a two-year project concluding May 9, 2027. This Project Grant supports research defining the urinary, biliary, and fecal excretion pathways of diverse per- and polyfluoroalkyl substances (PFAS) and investigating the impact of dietary fiber on PFAS elimination. The research...
- The National Institute of Environmental Health Sciences awarded the University of New England $163,856 on April 10, 2026, under the Environmental Health program (CFDA 93.113) to conduct a prospective study of per- and polyfluoroalkyl substance (PFAS) mixtures and pregnancy outcomes using data from the Study of Environment, Lifestyle, and Fibroids (SELF). The research leverages an existing cohort of reproductive-aged Black women from Detroit, Michigan, recruited between 2010 and 2012 when...
- The National Institute of Environmental Health Sciences awarded Silent Spring Institute, Inc., $154,700 on August 28, 2026, under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) to assess associations between per- and polyfluoroalkyl substance (PFAS) exposure from drinking water and hypertension and blood pressure among adults and children. The project will analyze measured and historically reconstructed serum PFAS concentrations in relation to blood...
- The National Institute of Environmental Health Sciences awarded The Pennsylvania State University $2.864 million on April 4, 2026, under the Environmental Health program (CFDA 93.113) to investigate how per- and polyfluoroalkyl substances (PFAS) alter microbial function and drive disease progression through disruption of the host-gut microbiome axis. The research addresses early-life PFAS exposure, a particular concern because developmental periods represent a critical window of vulnerability...
- The National Institute of Environmental Health Sciences awarded North Carolina State University $4,233,899 under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) on August 1, 2026, to evaluate per- and polyfluoroalkyl substances (PFAS) exposure and associated metabolic health effects across three North Carolina communities with contaminated drinking water supplies. The research examines PFAS-induced dyslipidemia and obesity in approximately 1,000...
- The National Institute of Environmental Health Sciences awarded Virginia Commonwealth University $426,938 on July 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate how lipid transport proteins mediate the biodistribution and accumulation of per- and polyfluoroalkyl substances (PFAS) in human tissues and cells. The three-part research program develops fluorescent and nuclear magnetic resonance binding assays to screen five representative lipid transport proteins against...
- Federal Project Grant Award Summary Brown University received a $463,850 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded on September 10, 2025, with a completion date of September 9, 2027. The award supports research investigating associations between prenatal per- and polyfluoroalkyl substances (PFAS) mixture exposure and long-term health outcomes in adulthood. The research leverages the New England...
- The National Institute of Environmental Health Sciences awarded Michigan State University $402,066 on September 27, 2025, under the Environmental Health program (CFDA 93.113) to investigate how the epicardium and the IRE1 signaling pathway mediate the effects of environmental chemical exposure on cardiac function. The project employs three-dimensional human heart organoids derived from induced pluripotent stem cells to model the impact of per- and polyfluoroalkyl substances (PFAS) on lipid...
- Federal Project Grant Summary Duke University received a $3.12 million Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded September 5, 2025, with completion scheduled for September 4, 2029. The research project, conducted at Duke's Durham, North Carolina campus, investigates the mechanisms by which per- and polyfluoroalkyl substances (PFAS) exposure damages placental function and fetal development...
The National Institute of Environmental Health Sciences awarded $662,340 to the University of Massachusetts on August 13, 2026, under the Environmental Health program (CFDA 93.113) to investigate how per- and polyfluoroalkyl substances (PFAS) disrupt exocrine pancreas development and function in early life stages and identify recovery pathways through mechanistic study of the NRF2 pathway using transgenic zebrafish embryos. The research employs transgenic Danio rerio (zebrafish) embryos to examine the role of oxidative stress and reactive oxygen species in PFAS-induced pancreatic malformation, specifically addressing how early-life xenobiotic exposures result in shortened exocrine pancreas with functional consequences for digestive enzyme production. The work seeks to establish mechanistic understanding of how redox stress damages the developing pancreas and predisposes humans to pancreatitis, pancreatic insufficiency, obesity, and diabetes mellitus. The study focuses on identifying therapeutic recovery pathways that could mitigate disease risk from early environmental exposure. Performance takes place in Hadley, Massachusetts. The award runs through June 30, 2031. The recipient is the University of Massachusetts, Amherst campus. The parent organization is Massachusetts University Of (UEI NUKSGRX9L885).
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $662.3k | 8/12/26 |