Project Grant R01ES039536
- This Cooperative Agreement awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program provides $373,534 to North Carolina State University to extend and maintain the GenX Exposure Study. The overarching goal is to strengthen the study infrastructure and continue providing timely information to communities impacted by per- and polyfluoroalkyl substances (PFAS) in the Cape Fear River basin. Key activities include...
- The National Institute of Environmental Health Sciences awarded the University of Wisconsin - Madison $3,343,688 on September 1, 2026, under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) to examine pathways of per- and polyfluoroalkyl substances (PFAS) exposure and their impacts on hyperlipidemia in a rural community impacted by land spreading of biosolids and sludge. The research addresses three gaps in PFAS science. The study will examine how lipid...
- Federal Project Grant Summary Duke University received a $3.12 million Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded September 5, 2025, with completion scheduled for September 4, 2029. The research project, conducted at Duke's Durham, North Carolina campus, investigates the mechanisms by which per- and polyfluoroalkyl substances (PFAS) exposure damages placental function and fetal development...
- The National Institute of Environmental Health Sciences awarded Silent Spring Institute, Inc., $154,700 on August 28, 2026, under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) to assess associations between per- and polyfluoroalkyl substance (PFAS) exposure from drinking water and hypertension and blood pressure among adults and children. The project will analyze measured and historically reconstructed serum PFAS concentrations in relation to blood...
- The National Institute of Environmental Health Sciences awarded Virginia Commonwealth University $426,938 on July 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate how lipid transport proteins mediate the biodistribution and accumulation of per- and polyfluoroalkyl substances (PFAS) in human tissues and cells. The three-part research program develops fluorescent and nuclear magnetic resonance binding assays to screen five representative lipid transport proteins against...
- The National Institute of Environmental Health Sciences awarded the University of New England $163,856 on April 10, 2026, under the Environmental Health program (CFDA 93.113) to conduct a prospective study of per- and polyfluoroalkyl substance (PFAS) mixtures and pregnancy outcomes using data from the Study of Environment, Lifestyle, and Fibroids (SELF). The research leverages an existing cohort of reproductive-aged Black women from Detroit, Michigan, recruited between 2010 and 2012 when...
- The National Institute of Environmental Health Sciences awarded the University of Southern California $1.256 million on April 10, 2026, under the Environmental Health program (CFDA 93.113) to conduct translational research on per- and polyfluoroalkyl substances (PFAS) and metabolic diseases. The award funds four interconnected research areas. Area 1 analyzes epidemiological data from over 50,000 participants across 18 diverse cohorts to examine PFAS associations with omics biomarkers and...
- The National Institute of Environmental Health Sciences awarded The Pennsylvania State University $2.864 million on April 4, 2026, under the Environmental Health program (CFDA 93.113) to investigate how per- and polyfluoroalkyl substances (PFAS) alter microbial function and drive disease progression through disruption of the host-gut microbiome axis. The research addresses early-life PFAS exposure, a particular concern because developmental periods represent a critical window of vulnerability...
- The National Institute of Environmental Health Sciences awarded New Mexico State University $177,460 on August 17, 2026, under the Environmental Health program (CFDA 93.113) to investigate the prevalence and health risks of per- and polyfluoroalkyl substances (PFAS) in New Mexico de facto water reuse systems. The project addresses PFAS contamination in drinking water sources resulting from de facto reuse of treated wastewater—the unintentional introduction of treated wastewater into downstream...
- The National Institute of Environmental Health Sciences awarded Biota Inc. $306,585 under the Environmental Health grant program (CFDA 93.113) on July 1, 2026, to develop an automated nanoparticle-based sample preparation platform for per- and polyfluoroalkyl substances (PFAS) analysis. The Phase I project establishes feasibility of a fully automated workflow that replaces labor-intensive solid-phase extraction methods in PFAS monitoring. The platform integrates advanced nanoparticle chemistry...
The National Institute of Environmental Health Sciences awarded North Carolina State University $4,233,899 under the NIEHS Superfund Hazardous Substances Basic Research and Education program (CFDA 93.143) on August 1, 2026, to evaluate per- and polyfluoroalkyl substances (PFAS) exposure and associated metabolic health effects across three North Carolina communities with contaminated drinking water supplies. The research examines PFAS-induced dyslipidemia and obesity in approximately 1,000 individuals ages six and older recruited from Pittsboro (exposed to historically used PFAS via the Cape Fear River), a private well community south of Fayetteville (exposed to novel PFAS through air transport from a manufacturing facility), and the lower Cape Fear area comprising New Hanover and Brunswick Counties (exposed to both historically used PFAS such as PFOA and PFOS and novel PFAS including GENX and Nafion byproduct 2). The study incorporates exposure reconstruction methodology to estimate health effects from past exposures to novel PFAS that are detectable in drinking water but not in human serum. The award runs through July 31, 2030, with place of performance in Raleigh, North Carolina. Work is conducted in collaboration with community groups along the Cape Fear River. The assistance type is a Project Grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $4.2m | 7/28/26 |