Project Grant R01ES038206
- Federal Grant Award Summary The Pennsylvania State University received a $110,124 Project Grant award, dated November 15, 2025, from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041). This collaborative research project, titled "ERASE-PFAS: Thermal Regeneration of PFAS-Laden Granular Activated Carbon," focuses on developing and validating thermal regeneration processes to enable the...
- Federal Grant Award Summary The Pennsylvania State University received a $450,000 Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems under the Engineering program (CFDA 47.041), effective September 1, 2025, through August 31, 2028. This NSF-BSF (National Science Foundation-Binational Science Foundation) collaborative award will develop organ-on-chip predictive models to investigate the role of gut microorganisms...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded The Pennsylvania State University a $249,000 Project Grant on August 12, 2025, under the Environmental Health program (CFDA 93.113) to conduct research examining the interaction between perinatal organophosphate flame retardant (OPFR) exposure and adult chronic stress on cognitive processing. The project, extending through July 31, 2028, will investigate how early developmental exposure to...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Southern California a Project Grant of $1.256 million under the Environmental Health program (CFDA 93.113) on April 10, 2026, for a translational research initiative examining per- and polyfluoroalkyl substances (PFAS) and metabolic diseases. The grant supports an eight-year research program (through March 31, 2034) organized into four interconnected research areas:...
- Federal Grant Award Summary North Carolina State University received a $927,778 Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded June 10, 2025, with a completion date of March 30, 2029. The project develops spatial and high-dimensional causal inference methods to estimate health effects of perfluoroalkyl and polyfluoroalkyl substances (PFAS) mixtures on population health. The research addresses...
- Federal Grant Award Summary The Pennsylvania State University received a $175,300 Project Grant from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310), awarded February 1, 2026, with completion targeted for January 31, 2028. The award funds the development of computer-based models to evaluate biodegradable food packaging coatings derived from natural materials such as starch and...
- Federal Grant Award Summary The National Science Foundation (NSF) Division of Environmental Biology awarded a $500K Project Grant (CFDA 47.074, Biological Sciences program) to The Pennsylvania State University effective July 1, 2025, through June 30, 2028. This research initiative, titled "BOCP-Design: US-China: Understanding the Evolutionary Mechanisms That Drive Human Microbiome Diversity," delivers foundational scientific research reconstructing the history of the human oral...
- Federal Project Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded a $124,728 Project Grant to the University of Pennsylvania on September 8, 2025, under the Environmental Health program (CFDA 93.113) to conduct research on gestational and childhood exposure to endocrine-disrupting chemicals (EDCs) and their effects on adolescent neurobehavior. The award, scheduled for completion by August 31, 2027, funds a phased research initiative investigating how...
- Federal Project Grant Award Summary Duke University received a $3.12M Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded September 5, 2025, with completion targeted for September 4, 2029. The research initiative investigates the mechanisms by which per- and polyfluoroalkyl substances (PFAS) exposure impairs placental function and fetal development through disruption of mitochondrial function and...
- Federal Grant Award Summary The National Institute of Environmental Health Sciences (NIEHS) awarded the University of Massachusetts Lowell $157,437 under the Environmental Health program (CFDA 93.113) on May 10, 2025, for a two-year project concluding May 9, 2027. This Project Grant supports research defining the urinary, biliary, and fecal excretion pathways of diverse per- and polyfluoroalkyl substances (PFAS) and investigating the impact of dietary fiber on PFAS elimination. The research...
The Pennsylvania State University received a $2.86M Project Grant from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), awarded April 4, 2026, with completion targeted for April 3, 2030. The research will investigate the mechanisms by which per- and polyfluoroalkyl substances (PFAS) influence host-microbiome interactions, with particular focus on early-life exposures during critical developmental windows. The project delivers research products including mechanistic studies of PFAS effects on gut microbiota function, bioaccumulation data across microbial species, and mouse model studies characterizing how early-life PFAS exposure disrupts the host-gut microbiome axis and contributes to adult metabolic disease. The research employs an interdisciplinary approach combining expertise in perfluorinated chemical toxicology, microbiology, metabolomics, and biostatistics to address identified gaps in understanding PFAS-induced microbiome toxicity. Specific Aim 1 will quantify microbial toxicity endpoints and adaptation mechanisms in health-critical bacterial species, while Specific Aim 2 will establish causal linkages between environmental PFAS exposure, microbiome disruption, and subsequent metabolic dysfunction in animal models. The work is conducted at Penn State's University Park, Pennsylvania facility and advances the NIEHS mission to translate environmental health knowledge into strategies reducing disease burden across vulnerable populations exposed to persistent environmental contaminants.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.9m | 4/2/26 |