This $398,838 Cooperative Agreement awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program supports research on the neurodevelopmental effects of exposure to flame retardants. The project aims to investigate how developmental exposure to the chemical mixture Firemaster 550 impacts the dopamine, oxytocin, and vasopressin receptor systems in the social brain neural network of prairie voles, a highly social...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program will fund a $719,892 research project at New York University (NYU) School of Medicine. The study aims to examine the relationship between prenatal and postnatal exposure to phthalates and bisphenols, common endocrine-disrupting chemicals, and infant reproductive development during the critical "minipuberty" period in the first six...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, provides $409,508 to Texas A&M AgriLife Research to study the impact of organophosphate flame retardant exposure on metabolic and brain aging. The key objectives are to define the extent to which triphenyl phosphate (TPHP) exposure contributes to metabolic and cognitive decline, by assessing effects on the gut microbiome, metabolome, and...
This federal Project Grant award of $695,853, provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program, supports research on the impact of per- and polyfluoroalkyl substances (PFAS) exposures during the perinatal period on children's development. The project aims to investigate the mechanisms by which prenatal PFAS exposures affect placental function and child growth and neurodevelopment, as well as explore whether...
This Project Grant award of $171,064.00 from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program supports research to investigate how polychlorinated biphenyls (PCBs) alter the communication between adipocytes (fat cells) and macrophages (immune cells) in adipose tissue. The research aims to uncover the mechanisms by which PCB exposure disrupts adipose tissue function and contributes to metabolic disorders like...
This federal Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $159,200 to the University of California, San Diego (UCSD) to characterize the role of oxidation-reduction (redox) signaling in normal forebrain neurodevelopment in mice and its response to environmental exposures. Specifically, the researchers will use a genetically encoded redox-sensitive fluorescent biosensor to determine the redox...
This federal Project Grant award, valued at $561,584.00 and effective from December 13, 2024 to October 31, 2029, was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) federal grant program. The funding will support research conducted by Rutgers, The State University of New Jersey, to investigate the ovarian disrupting effects of per- and polyfluoroalkyl substances (PFAS) on female reproductive health and fertility. The...
This $176,270 Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program will fund research by San Diego State University Foundation to investigate the toxic effects of the industrial solvent trichloroethylene and its metabolite on placental cells at the maternal-fetal interface. The research aims to identify molecular factors underlying disruptions to placental function that can lead to adverse birth outcomes...
This Project Grant award of $605,550 from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports research to explore the impact of developmental exposure to pyrethroid pesticides on neurodevelopmental outcomes in prairie voles. The primary objectives are to: 1) assess dose-dependent behavioral and molecular effects of developmental deltamethrin exposure in controlled laboratory assays, 2) evaluate dose-dependent changes to...
This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $1,968,864 to Purdue University to evaluate and compare the neurotoxicity of per- and polyfluoroalkyl substances (PFAS), including legacy chemicals like PFOA and replacement compounds like PFBA and GenX. The research aims to determine how low-dose developmental PFAS exposure disrupts neuronal communication and increases vulnerability to...