Project Grant R01ES024381

This Project Grant award by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) Federal Grant Program provides funding of $429,135 to The University of Kentucky Research Foundation to conduct research on the mechanisms of sex-specific metabolic disruption caused by exposure to the organophosphate flame retardant tris(1,3-dichloro-2-propyl) phosphate (TDCPP). The objective is to determine if activation of the pregnane X receptor (PXR)...

This $857,216 federal Project Grant award from the National Institute of Mental Health (NIMH) under CFDA 93.242 Mental Health Research Grants will be used by Boston Children's Hospital to conduct a longitudinal study examining the neurodevelopmental trajectories and social determinants leading to early symptoms of Attention Deficit Hyperactivity Disorder (ADHD) and disruptive behaviors in children. The study will leverage an existing large, diverse cohort of low-resourced infants seen in an...

The National Institute of Environmental Health Sciences (NIEHS) awarded a $605,550 Project Grant under the Environmental Health (CFDA 93.113) program to the University of Toledo Health Science Campus Division for a study titled "Developmental Pyrethroid Exposure in the Prairie Vole as a Model of Environmental Risk for Autism." The project aims to explore the maximum safe developmental dose of the pyrethroid pesticide deltamethrin and its effects on neurodevelopmental outcomes in...

This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) Federal Grant Program, provides $719,892 to New York University School of Medicine to conduct research on the effects of phthalate and bisphenol exposure on infant reproductive development during the "minipuberty" period in the first six months of life. The study will evaluate associations between maternal prenatal exposure, infant postnatal...

The National Institute of Environmental Health Sciences (NIEHS) awarded a $639,686 Project Grant under the Environmental Health (CFDA 93.113) Federal Grant Program to the University of Cincinnati. The purpose of the grant is to conduct a longitudinal study investigating the impact of fluoride exposure during critical developmental windows, from the prenatal period through early childhood, on neurodevelopment, cognition, neurobehavior, and brain structure in adolescence. The study will leverage...

This Project Grant award with ID R01ES035518 was provided by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health federal grant program (CFDA 93.113). The award totals $688,904 and has an ultimate project completion date of July 31, 2029. The overall objective of this grant is to increase understanding of the gene-environment interactions that link developmental manganese exposure, dopamine dysregulation, and the increased frequency of ADHD diagnoses....

This $421,047 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program supports research on the interaction between genetic and environmental risk factors for autism and other neurodevelopmental disorders. The principal investigator will use the prairie vole, a rodent species with complex social behaviors, to study how exposure to the pyrethroid pesticide deltamethrin during pregnancy and lactation impacts...

This Project Grant award from the National Institute of Environmental Health Sciences (NIEHS), under the Environmental Health (CFDA 93.113) program, aims to define the neurotoxic and neurodevelopmental health risks associated with exposure to per- and polyfluoroalkyl substances (PFAS). The $546,350 grant, awarded on January 13, 2025, will support a research study to investigate the mechanisms of PFAS uptake by neurons, the neurotoxic effects of PFAS exposure, and the impacts of PFAS on...

This Cooperative Agreement award from the National Institute of Environmental Health Sciences (NIEHS), part of the Environmental Health (CFDA 93.113) federal grant program, provides $398,838 to North Carolina State University (NC State) to investigate the neurodevelopmental effects of exposure to flame retardants. The key objectives are to: 1) Evaluate how developmental exposure to the flame retardant mixture Firemaster 550 impacts the density and gene expression of dopamine, oxytocin, and...

This Project Grant awarded by the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health (CFDA 93.113) program provides $776,150.33 to the University of Massachusetts to investigate the relationship between exposure to the antimicrobial and endocrine-disrupting compound triclosan, pubertal hormones, the adolescent gut microbiome, and neurobehavior. The project aims to identify windows of susceptibility to triclosan exposure, assess the role of hormones in...