Project Grant R01EB038575
- The National Institute of Neurological Disorders and Stroke awarded the University of Alabama at Birmingham $237,870 on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to localize cerebral epileptiform activity during stereoelectroencephalography monitoring. Approximately one-third of epilepsy patients are drug-resistant and candidates for surgical intervention. Successful epilepsy surgery depends on accurate localization...
- The National Institute of Neurological Disorders and Stroke awarded a $168,714 cooperative agreement to the University of Florida on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds the University of Florida Early Research Program for Neurology and Neurosurgery Residents, which develops a comprehensive early research pipeline engaging neurology and neurosurgery residents in research from the start of...
- The National Institute of Neurological Disorders and Stroke awarded Duke University $555,895 on July 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the biophysical mechanisms of temporal interference stimulation on epileptic discharges in the human brain. The research, conducted at the Comprehensive Epilepsy Center at Duke University in Durham, North Carolina, will leverage stereo-electroencephalography...
- The National Institute of Neurological Disorders and Stroke awarded the University of Alabama at Birmingham $567,358 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop single-pulse electrical stimulation (SPES) protocols for improving surgical outcomes in drug-resistant epilepsy. The project addresses limitations in current SPES clinical utility by applying dynamical systems and control theory to enhance...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded The General Hospital Corporation (Massachusetts General Hospital) $234,070 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds a five-year mentored patient-oriented research career development program (K23 mechanism) investigating how direct electrical...
- The National Institute of Child Health and Human Development awarded the University of Miami $307,000 on September 1, 2026, under the Child Health and Human Development Extramural Research program (CFDA 93.865) to validate scalp electroencephalography (EEG) features for rehabilitative brain-computer interface (BCI) applications using concurrent intracranial EEG as ground truth. The project addresses a critical gap in non-invasive motor rehabilitation technologies. While invasive intracranial EEG...
- The National Institute of Neurological Disorders and Stroke awarded the University of Pennsylvania $646,295 on June 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, R01NS148413) to develop quantitative methods for measuring seizure spread and interictal abnormalities on scalp and intracranial electroencephalography (EEG) to improve identification of focal versus diffuse epileptic networks and guide surgical planning for...
- The National Institute of Biomedical Imaging and Bioengineering awarded Florida State University $607,832 on September 2, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop and validate an automated video-based assessment tool for laparoscopic surgical skills using deep learning technologies. The project will create a deep learning-based video assessment network (VBA-NET) to deliver both summative and formative...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $577,611 on January 23, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate how cell-specific neural activity contributes to resting-state functional magnetic resonance imaging (rs-fMRI) patterns in the brain. The research develops and deploys simultaneous wide-field optical imaging (WOI) and rs-fMRI methodology to detect...
- The National Institute of Neurological Disorders and Stroke awarded the University of Miami $581,794 on September 7, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research into inflammasome activation and its role in the foreign body response triggered by chronically implanted microelectrodes in neural tissue. Microelectrode implants enable neuroprosthetic and neuromodulation technologies for patients with...
The National Institute of Biomedical Imaging and Bioengineering awarded the University of Florida $572,193 on September 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop and validate a multimodal presurgical language mapping framework for epilepsy surgery patients. The project integrates four complementary neuroimaging and mapping modalities—functional MRI, magnetoencephalography, high-gamma modulation, and diffusion-weighted imaging—to reduce postoperative language deficits in drug-resistant epilepsy patients undergoing surgical resection. Current electrical stimulation mapping, the clinical standard, fails to prevent language impairment in more than 25 percent of cases and carries risks of seizures, after-discharges, and prolonged testing time. The first aim evaluates high-gamma modulation combined with electrical stimulation mapping through retrospective analysis to identify language domains overlooked by electrical stimulation alone and prospective study to assess whether high-gamma-informed mapping improves postoperative outcomes compared to anatomy-informed mapping. The second aim develops machine learning-based support vector machine models to enhance language prediction. Work is performed in Gainesville, Florida, with a period of performance through July 31, 2030. The University of Florida Division of Sponsored Research receives and administers the award as prime recipient.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $572.2k | 8/25/26 |