Project Grant R01NS148413
- Federal Project Grant Award Summary The University of Pennsylvania received a $231,325 Project Grant awarded July 10, 2025, by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports a five-year research initiative (through June 30, 2030) investigating the neurophysiologic signatures of essential tremor and the mechanisms by which deep brain stimulation...
- Federal Grant Award Summary The University of Pennsylvania received a $149,190 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective August 6, 2026, with completion anticipated by December 31, 2028. The award funds research to elucidate the mechanistic role of inositol 1,4,5-trisphosphate receptor type 1 (IP3R1) in synaptic transmission...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $438,836 to The Trustees of the Stevens Institute of Technology under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The award supports research to develop a unified paradigm using simultaneous multimodal measurement of scalp EEG and intracranial EEG (iEEG) signals to estimate the electrophysiological networks of the whole brain....
- Federal Grant Award Summary Vanderbilt University Medical Center received a $545,319 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded August 15, 2025, with completion targeted for July 31, 2030. The Sahel Epilepsy Epidemiology and Genomics Study (SEEG) delivers epidemiological and genetic research services to address critical gaps in epilepsy...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Pennsylvania a Project Grant totaling $198,164.00, effective December 1, 2025, through May 30, 2028, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This award supports fundamental research investigating the pathophysiology of SCN3A-related neurodevelopmental disorder (SCN3A-NDD), a newly identified genetic...
- The University of Alabama at Birmingham received a $237,870 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded June 1, 2026, with a completion date of May 31, 2031. This research initiative focuses on developing and validating electroencephalogram (EEG) source localization techniques applied to stereoelectroencephalography (SEEG) recordings...
- Federal Project Grant Award Summary The University of Pennsylvania received a $664,458 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective September 1, 2025, through August 31, 2030. This award supports the development and validation of a novel optical imaging technology for prehospital detection of large vessel occlusion (LVO) in acute stroke...
- Federal Project Grant Award Summary The University of Pennsylvania received a $667,349 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective August 1, 2025, through June 30, 2030. This award funds research investigating state-dependent control of nociception in opioid circuits, specifically examining how pain perception is modulated by...
- Federal Grant Award Summary Award Overview: New York University School of Medicine received a $247,994 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective March 1, 2026 through April 30, 2031. The award supports research led by Dr. Andrew Michalak, an Assistant Professor of Neurology at NYU Grossman School of Medicine, focused on advancing...
- Federal Grant Award Summary The National Science Foundation's Division of Electrical, Communications and Cyber Systems awarded $448,039 to the University of Pennsylvania under the Engineering program (CFDA 47.041) to develop an innovative ear-based wearable device for seizure monitoring in epilepsy patients. The project, which commenced October 1, 2025 and concludes September 30, 2028, focuses on engineering a wireless "earable" featuring electroencephalography (EEG) electrodes...
Federal Grant Award Summary The University of Pennsylvania received a $646,295 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded June 15, 2026, with completion targeted for May 31, 2031. The grant funds research to develop quantitative methods for assessing seizure network characteristics in patients with drug-resistant epilepsy, addressing the critical clinical challenge of determining whether patients have focal or diffuse epileptic networks. The project deliverables include optimized analytical tools to measure seizure spread and interictal abnormalities from intracranial electroencephalography (IEEG) and scalp electroencephalography (EEG) data, integration of these measurements to predict network focality and surgical outcomes, and combined analysis methodologies that leverage both IEEG and scalp EEG data modalities. This research is designed to enable non-invasive, scalable assessments of network focality that can reduce unnecessary invasive procedures and guide patients toward appropriate therapeutic interventions—either curative brain surgery for focal networks or palliative neuromodulatory device therapy for diffuse networks. By developing and validating these quantitative diagnostic tools, the project aims to improve surgical planning outcomes and reduce postoperative seizure recurrence in this patient population.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $646.3k | 6/3/26 |