Project Grant K23NS151798
- The National Institute of Neurological Disorders and Stroke awarded Baylor College of Medicine $100,228 on September 30, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop optimized neurostimulation patterns for seizure control in drug-resistant epilepsy. The recipient will design and validate a novel platform combining high-entropy stimulus generation and deep learning to optimize complex pulse sequences with...
- The National Institute of Neurological Disorders and Stroke awarded the Epilepsy Foundation of America $491,786 on September 15, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to plan epilepsy health disparities research through community co-production. The recipient will develop methods to engage local community partners and epilepsy patient and family partners in co-producing research priorities for epilepsy health disparities...
- The National Institute of Neurological Disorders and Stroke awarded Duke University $555,895 on July 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the biophysical mechanisms of temporal interference stimulation on epileptic discharges in the human brain. The research, conducted at the Comprehensive Epilepsy Center at Duke University in Durham, North Carolina, will leverage stereo-electroencephalography...
- The National Institute of Neurological Disorders and Stroke awarded The General Hospital Corporation (Massachusetts General Hospital) $629,733 on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support research into the mechanisms of magnetic activation of neurons. The research combines engineering, electrophysiological recordings, and computational modeling to systematically study how induced electromagnetic fields...
- The National Institute of Neurological Disorders and Stroke awarded New York University $247,994 on March 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support research on ictal onset patterns and responsive neurostimulation outcomes in drug-resistant epilepsy. Dr. Andrew Michalak, an assistant professor of neurology at New York University Grossman School of Medicine, leads the project. The research explores the basic...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services, awarded Boston Children's Hospital $577,573 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds functional validation of candidate genes implicated in refractory focal epilepsy, with emphasis on mosaic variants in mTOR pathway genes and non-mTOR genes such as SLC35A2. Boston Children's...
- The National Institute of Neurological Disorders and Stroke, an operating division of the National Institutes of Health under the Department of Health and Human Services, awarded $646,706 to Icahn School of Medicine at Mount Sinai on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research to develop and validate magnetic resonance elastography and arterial spin labeling as novel complementary...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded Emory University $420,142 on May 4, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to explore the contribution of extracellular vesicles to epileptogenesis in temporal lobe epilepsy and Dravet syndrome. The research examines how extracellular vesicles—small membranous particles...
- The National Institute of Neurological Disorders and Stroke awarded The General Hospital Corporation (doing business as Massachusetts General Hospital) $511,402 on February 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop non-invasive transcutaneous vagus nerve stimulation as a novel neuromodulatory intervention targeting aneurysmal subarachnoid hemorrhage. The project will test whether non-invasive vagus nerve...
- The National Institute of Neurological Disorders and Stroke awarded Icahn School of Medicine at Mount Sinai $150,512 on August 5, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research into controlling epilepsy symptoms through precisely timed inhibition and circuit editing, focused on temporal lobe epilepsy and cognitive impairments associated with seizure disorders. The research employs closed-loop...
The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded The General Hospital Corporation (Massachusetts General Hospital) $234,070 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds a five-year mentored patient-oriented research career development program (K23 mechanism) investigating how direct electrical stimulation affects epileptiform activity in the human brain. The mentored researcher will conduct three research activities: analyze seizure characteristics in patients undergoing intracranial EEG epilepsy monitoring with direct electrical stimulation to determine whether stronger brain connectivity via white matter connections correlates with greater seizure induction; prospectively stimulate the thalamus at varying frequencies and durations to examine whether stronger brain connectivity with inhibitory stimulation associates with decreased epileptiform activity; and examine mechanisms by which stimulation terminates seizures. The research aims to improve therapeutic neurostimulation device efficacy and enable more rapid, predictable, and consistent seizure control in medication-refractory epilepsy patients. Performance occurs in Boston, Massachusetts from September 1, 2026 through August 31, 2031. The award obligates $234,070 in total funding.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $234.1k | 8/31/26 |