The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $2,278,167 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to the University of North Carolina at Chapel Hill (UNC-CH) and the California Institute of Technology (Caltech). The grant aims to develop non-invasive, ultra-high precision transcranial ultrasound surgery techniques for treating brain tumors, such as glioblastoma...
This Project Grant award from the National Eye Institute (CFDA 93.867 Vision Research) provides $462,000 to the University of Utah to develop a non-human primate model capable of measuring real-time changes in neural activity after ultrasound neuromodulation. The study aims to deliver clinic-ready protocols to optimally excite or inhibit targeted brain regions, with the goal of revolutionizing treatments for neurological and mental disorders through precise, non-invasive ultrasound...
This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $423,151 to Duke University to develop a new functional brain imaging technology using super-resolution ultrasound. The goal is to create a radiation-free, low-cost system that can noninvasively map deep brain neural activities at high spatial and temporal resolutions. The award period runs from January 1, 2025 to April 30, 2028. The research plan includes three technical thrusts: 1)...
The National Science Foundation (NSF) awarded a $512,275 Project Grant to the University of Utah to develop a focused ultrasound system for the noninvasive repair of damaged neural pathways. The project, funded under NSF's Engineering program (CFDA 47.041), aims to create a therapeutic tool that can modulate neural connectivity in the human brain, with the potential to enable rehabilitation for individuals affected by neurological and mental health conditions. The research team, comprising an...
The National Institute of Mental Health (NIMH) awarded a $215,343 Project Grant (CFDA 93.242 - Mental Health Research Grants) to the Laureate Institute For Brain Research, LLC in Tulsa, Oklahoma. The grant will fund a 2-year research project titled "Dose-Dependent Functional Connectivity Effects of Low-Intensity Focused Ultrasound Applied to Deep White Matter Tracts in Humans." The project aims to define the dose-dependent effects of low-intensity focused ultrasound (LIFU) applied to...
The National Institute of Neurological Disorders and Stroke (NINDS), through its Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), awarded a $578,701 project grant to the University of California, Los Angeles (UCLA) on June 16, 2025. The goal of this 5-year project is to develop a near-infrared confocal squeezed light-field microscopy (SLIM) system capable of kilohertz volumetric imaging of neuronal action potentials in 3D. This technology is intended to...
The National Institutes of Health National Institute of Neurological Disorders and Stroke awarded $1,852,675 under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies program (CFDA 93.372) to the University of California, Los Angeles from August 1, 2022 to July 31, 2025. The award will support the development of light field tomographic microscopy for kilohertz volumetric imaging of neuronal action potentials in awake behaving mice. Specifically, the...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $649,965 to The Regents of the University of California, San Francisco (UCSF) from December 1, 2024 to October 31, 2029. The funding supports research to identify specific connections between the basolateral amygdala and ventral hippocampus that generate a biomarker of beta-frequency synchronization associated with mood and anxiety. The...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a 3-year, $3,582,963 Project Grant under the 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372) to Carnegie Mellon University (CMU). The grant supports the development and validation of novel wearable transcranial focused ultrasound (TFUS) neuromodulation transducer array probes compatible with simultaneous electrophysiological recordings in behaving...
This $600,000 Project Grant from the National Science Foundation's Division of Information and Intelligent Systems, under the Computer and Information Science and Engineering program (CFDA 47.070), will fund research at The Pennsylvania State University to develop a fully wireless, flexible electrical-acoustic implant for high-resolution neural stimulation and recording across large-scale brain circuits. The implant is intended to provide minimally invasive ultrasound neuromodulation and...