Project Grant R01DK144741
- Federal Project Grant Award Summary Award Overview New York University received a $249,000 Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective July 1, 2025, through June 30, 2028. The award supports basic biomedical research investigating the competing neurobiological mechanisms by which hunger-promoting AGRP (Agouti-Related Peptide) neurons and...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded The Trustees of Columbia University in the City of New York a Project Grant of $801,009 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), effective September 11, 2025, with a completion date of June 30, 2030. The research focuses on elucidating the distinct roles of vascular sympathetic neurons (VSN) in brown adipose tissue (BAT) and their...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $167,363 Project Grant to the University of California, Los Angeles, effective March 1, 2026, through February 28, 2031, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research focuses on identifying novel central nervous system (CNS) mechanisms to combat obesity by investigating how specific neurons in the paraventricular nucleus...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded The Trustees of Columbia University in the City of New York a Project Grant of $746,950 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) effective March 1, 2026, through February 28, 2031. This award funds basic biomedical research investigating the metabolic effects of manganese (Mn) and its role in regulating the protein kinase AKT, a...
- Federal Project Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $196,460 Project Grant to The Trustees of Columbia University in the City of New York (Health Sciences Division) on June 23, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports investigator-initiated biomedical research designed to improve understanding of disease mechanisms and develop improved prevention,...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $296,676 Project Grant to the University of Pennsylvania on June 19, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). This biomedical research project, titled "Dissecting the Gut-Hypothalamus Axis for Fructose Sensing" and scheduled for completion by December 31, 2027, investigates the neural mechanisms through which...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded The Washington University a Project Grant totaling $720,353 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) on March 25, 2026, with a completion date of January 31, 2031. This award funds basic biomedical research investigating neural circuits in the preoptic hypothalamus that regulate energy expenditure and metabolism. The research focuses...
- Federal Project Grant Award Summary Duke University's Office of Research Administration has been awarded $637,471 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) administered by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The project grant, initiated April 1, 2026, and scheduled for completion January 31, 2030, supports basic biomedical research aimed at elucidating the mechanisms by which the gastrointestinal tract...
- Federal Project Grant Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded The Trustees of Columbia University in the City of New York a Project Grant totaling $246,750 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award, effective August 15, 2025, through August 14, 2027, funds research investigating the mechanisms of pancreatic inflammation in obesity. The research addresses how obesity alters...
- Federal Grant Award Summary The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded $549,602 to University Enterprises Corporation at California State University, San Bernardino under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) for a three-year project period from May 1, 2026 through April 30, 2029. This Project Grant funds research designed to uncover neural, psychological, and physiological mechanisms underlying hunger and...
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded Columbia University's Health Sciences Division a $838,425 Project Grant effective May 1, 2026, through March 31, 2031, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research project focuses on nutrient sensing in pro-opiomelanocortin (POMC) neurons and the mechanisms by which glucose and lactate regulate these hypothalamic neurons to control feeding behavior and whole-body energy metabolism. The research will investigate how lactate, a circulating glucose metabolite, activates POMC neurons in conjunction with glucose to modulate satiety signals and metabolic homeostasis, with particular attention to the roles of lactate dehydrogenase enzymes and mitochondrial metabolism in this signaling pathway. This basic science research project advances NIDDK's strategic priority to support investigator-initiated research that elucidates disease mechanisms and identifies therapeutic targets relevant to diabetes and metabolic disorders. The award enables Columbia University to conduct experiments examining nutrient-sensing pathways in the brain that fundamentally regulate feeding and glucose metabolism, contributing to the scientific foundation necessary for developing improved prevention and treatment approaches for metabolic diseases.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $838.4k | 5/1/26 |