Project Grant R03DK140421
Award Date 8/15/25
Completion Date 8/14/27
Dollars Obligated $247K
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
New York, USA
Similar Awards
- This federal Project Grant award of $196,460 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will support research to determine how inhibiting the migration of immature neutrophils during obesity affects hematopoietic stem and progenitor cells, metabolism, and systemic inflammation. The award, made on Jun 23, 2025, is to The Trustees of Columbia University in the...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $734,612.00 to conduct research on the mechanisms through which stress and obesity reprogram monocyte and macrophage populations in response to elevated glucocorticoid levels. The research aims to elucidate how glucocorticoids induced by early-life stress and diet-induced...
- This federal Project Grant award of $147,486 from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) will fund research to investigate the role of gut microbes in regulating interleukin-22 (IL-22) levels in the pancreas and the impact on pancreatic health and disease. The research aims to determine how gut microbe-induced IL-22 affects pancreatic gene expression and the underlying cellular mechanisms, as well as the beneficial and detrimental effects of this...
- This $233,250 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) supports research to understand how macrophage branched chain amino acid (BCAA) metabolism contributes to obesity-related metabolic dysfunction. The project, led by The Washington University, will investigate the role of the enzyme protein phosphatase 1K (PPM1K) in regulating macrophage BCAA metabolism and...
- This $3,255,832 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847) will support research at the University of Chicago to investigate the role of macrophages in weight loss-induced metabolic health and adipose tissue inflammation resolution. The project aims to determine the phenotype, function, and transcriptome of visceral and subcutaneous adipose tissue macrophages across mouse and human models, as well as test strategies like cell...
- This $3,065,252 federal Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The project aims to develop engineered metabolite-based nanoparticles for immunomodulation of macrophages to treat obesity, a critical health concern due to its links to metabolic diseases. The Terasaki Institute for Biomedical Innovation, a non-profit research...
- This $108,486 Project Grant award, funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to identify novel immune markers associated with obesity-driven diseases. The objective is to utilize novel tools to study the inter-organ communication pathway between the intestine and adipose tissue immune cells. The research leverages a Cre-inducible...
- This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), provides $176,500.00 to the University of Washington to investigate the links between hypothalamic microglia activation and perineuronal net (PNN) loss in the arcuate nucleus, and how these changes contribute to the pathogenesis of diet-induced obesity and glucose regulation. The...
- This federal Project Grant award of $813,511 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research at the Dana-Farber Cancer Institute, Inc. (DFCI) to investigate the structural basis and functional consequences of thermogenic mitochondrial respiratory complexes assembly in the context of obesity and type 2 diabetes. The research aims to...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $773,112 Project Grant to Rockefeller University on September 5, 2025 under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to investigate the mechanisms of transcriptional control in adipocyte formation and function through nuclear receptor coactivators. The research aims to provide a better understanding of dysregulation in energy storage...